ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives 2-Chloromethyl-3,4-dimethoxypyridinium chloride

2-Chloromethyl-3,4-dimethoxypyridinium chloride

2-Chloromethyl-3,4-dimethoxypyridinium chloride Basic information
Product Name:2-Chloromethyl-3,4-dimethoxypyridinium chloride
Synonyms:2-(CHLOROMETHYL)-3,4-DIMETHOXY PYRIDINE HCL;2-CHLOROMETHYL-3,4-DIMETHOXY PYRIDINE HYDROCHLORIDE;2-Chloromethyl-3,4-dimethoxypyridinium chloride;2-(CHLOROMETHYL)-3,4-DIMETHOXYPYRIDINIUM HYDROCHLORIDE;2-Chloromethyl-3,4-dimethoxypyridinium chloride 72830-09-2;72830-09-2 2-Chloromethyl-3,4-dimethoxypyridinium chloride;-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride;alpha-Chloro-3,4-dimethoxy-2-picoline hydrochloride
CAS:72830-09-2
MF:C8H11Cl2NO2
MW:224.08
EINECS:416-440-5
Product Categories:Heterocycle-Pyridine series;(intermediate of pantoprazole);C7 and C8Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines;Bases & Related Reagents;Nucleotides
Mol File:72830-09-2.mol
2-Chloromethyl-3,4-dimethoxypyridinium chloride Structure
2-Chloromethyl-3,4-dimethoxypyridinium chloride Chemical Properties
Melting point 155 °C (dec.)(lit.)
storage temp. Inert atmosphere,Room Temperature
Water Solubility Soluble in water
solubility Chloroform (Slightly, Heated), Methanol (Very Slightly)
form powder to crystal
color White to Orange to Green
BRN 5360726
InChIKeyYYRIKJFWBIEEDH-UHFFFAOYSA-N
CAS DataBase Reference72830-09-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,N,Xi
Risk Statements 21/22-38-41-43-48/22-51/53
Safety Statements 26-36/37/39-61-2
RIDADR UN 3077 9/PG 3
WGK Germany 3
Hazard Note Irritant
HazardClass 9
PackingGroup III
HS Code 2933399932
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Chloromethyl-3,4-dimethoxypyridinium chloride Usage And Synthesis
Chemical PropertiesLight Brown Solid
Uses2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride may be used as a precursor for the preparation [(2-pyridyl)-2-ethyl]-[3,4-dimethoxy-(2-pyridylmethyl)]-N-methylamine.
General Description2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride (CDP) can be synthesized using maltol as a starting material. CDP and DMS (dimethyl sulfate) are used in the preparation of pantoprazole sodium (PPS), an antiulcerative drug. The quantification of CDP and DMS in PPS can be done simultaneously by gas chromatography–mass spectrometry (GC-MS) method.
2-Chloromethyl-3,4-dimethoxypyridinium chloride Preparation Products And Raw materials
Raw materials3,4-DIMETHOXY-2-METHYLPYRIDINE N-OXIDE-->3,4-Dimethoxy-2-pyridinemethanol
N-Methyl Pantoprazole, mixture of 1 and 3 isomers 4,4'-Bis(chloromethyl)-2,2'-bipyridyl 2-(2-AMINO-5-BROMOBENZOYL) PYRIDINE 2-Hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole Pantoprazole Impurity 11 2-Chloromethyl-3-methyl-4-(3-methoxypropoxy)pyridine hydrochloride 2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride 2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole Ufiprazole 4-Difluoromethoxy-2-nitro-aniline p-Anisic acid N-[4-(difluoromethoxy)-2-nitrophenyl]acetamide Sodium erythorbate Pyridine hydrochloride 2-(Chloromethyl)pyridine 2-CHLOROMETHYL-3,4-DIMETHOXY PYRIDINE HYDROCHLORIDE Pantoprazole
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