ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole

1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole

1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole Basic information
Product Name:1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole
Synonyms:1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole;Posaconazole Impurity 94;1H-1,2,4-Triazole, 1-[[2-(2,4-difluorophenyl)tetrahydro-4-[(phenylmethoxy)methyl]-2-furanyl]methyl]-, (2R-cis)- (9CI);Posaconazole Impurity 91;PosacozoleImpurity66
CAS:165115-83-3
MF:C21H21F2N3O2
MW:385.41
EINECS:
Product Categories:
Mol File:165115-83-3.mol
1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole Structure
1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole Chemical Properties
Boiling point 515.6±60.0 °C(Predicted)
density 1.28±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Ethyl Aceate (Slightly)
form Oil
pka2.75±0.10(Predicted)
color Colorless
Safety Information
MSDS Information
1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole Usage And Synthesis
Uses1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole is an impurity of Posaconazole (P689600), an orally active triazole antifungal.
1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole Preparation Products And Raw materials
Preparation ProductsD-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-
1-[1-(Bromomethyl)ethenyl]-2,4-difluoro-benzene PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one, Posaconazole Impurity 64 Hydrazine, [1-ethyl-2-(phenylmethoxy)propyl]-,[S-(R*,R*)]-(9CI) Posaconazole Impurity 50 1-(4-Methoxyphenyl)piperazine 1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Posaconazole Impurity 42 Posaconazole Impurity 47 1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine 4-([4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-CARBAMIC ACID PHENYL ESTER D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- Posaconazole Impurity 51 4-Methylbenzenesulfonhydrazide Posaconazole Impurity 51 Posaconazole Impurity 43
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