|
| | Syringic acid Basic information |
| | Syringic acid Chemical Properties |
| Melting point | 205-209 °C (lit.) | | Boiling point | 192-193°C 14mm | | density | 1.2539 (rough estimate) | | refractive index | 1.4570 (estimate) | | Fp | 192-193°C/14mm | | storage temp. | Store below +30°C. | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 4.33±0.10(Predicted) | | form | Powder | | color | Grayish-beige to light brown | | Water Solubility | 5780 mg/L (25 ºC) | | BRN | 2115262 | | Stability: | Stable. Incompatible with strong bases, strong oxidizing agents. | | InChIKey | JMSVCTWVEWCHDZ-UHFFFAOYSA-N | | LogP | 1.040 | | CAS DataBase Reference | 530-57-4(CAS DataBase Reference) | | NIST Chemistry Reference | Benzoic acid, 4-hydroxy-3,5-dimethoxy-(530-57-4) | | EPA Substance Registry System | Syringic acid (530-57-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | RTECS | DH2090000 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29189090 |
| | Syringic acid Usage And Synthesis |
| Description | Syringic acid is a naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol. It is also a component of phenolic extracts from various plants that have antioxidant and prooxidant activities. Syringic acid has been shown to inhibit aldose reductase (IC50 = 213 μg/ml), proteasome activity, and cancer cell proliferation. Phenolic extracts containing syringic acid have been shown to inhibit α-amylase and α-glucosidase activities and reduce lipid peroxidation in vitro. | | Chemical Properties | light brown powder | | Uses | antiproliferative; antifungal | | Uses | Syringic Acid is used in biological studies for electron transfer from plant phenolates to carotenoid radical cations with antioxidant interaction entering the Marcus theory inverted region. | | Definition | ChEBI: A dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid. | | Purification Methods | Recrystallise syringic acid from H2O using charcoal [Bogert & Coyne J Am Chem Soc 51 571 1929, Anderson & Nabenhauer J Am Chem Soc 48 3001 1926.] The methyl ester has m 107o (from MeOH), the 4-acetyl derivative has m 190o and the 4-benzoyl derivative has m 229-232o. [Hahn & Wassmuth Chem Ber 67 2050 1934, UV: Lemon J Am Chem Soc 69 2998 1947 and Pearl & Beyer J Am Chem Soc 72 1743 1950, Beilstein 10 IV 1995.] |
| | Syringic acid Preparation Products And Raw materials |
|
