Boc-L-Glutamic acid

Boc-L-Glutamic acid Basic information

Product Name:	Boc-L-Glutamic acid
Synonyms:	N-(TERT-BUTOXYCARBONYL)-L-GLUTAMIC ACID;N-T-BUTOXYCARBONYL-L-GLUTAMIC ACID;N-ALPHA-T-BOC-L-GLUTAMIC ACID;N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID;N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID;BOC-GLU-OH;BOC-GLUTAMIC ACID-OH;BOC-L-GLU-OH
CAS:	2419-94-5
MF:	C10H17NO6
MW:	247.25
EINECS:	1533716-785-6
Product Categories:	Glutamic acid [Glu, E];Boc-Amino Acids and Derivative;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids;Boc-Amino acid series;Amino Acid Derivatives;Amino Acids
Mol File:	2419-94-5.mol

Boc-L-Glutamic acid Chemical Properties

Melting point	~110 °C (dec.)
alpha	-15 º (c=1, CH30H)
Boiling point	390.28°C (rough estimate)
density	1.2868 (rough estimate)
refractive index	-15 ° (C=1, MeOH)
storage temp.	2-8°C
Water Solubility	Soluble in water
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka	3.83±0.10(Predicted)
form	powder to crystal
color	White to Almost white
optical activity	[α]20/D 14.5±2°, c = 1% in methanol
BRN	2418563
CAS DataBase Reference	2419-94-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	22-24/25-36-26-4/25
WGK Germany	3
HS Code	29241990

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

Boc-L-Glutamic acid Usage And Synthesis

Chemical Properties

white to off-white crystalline powder

Uses

N-Boc-L-glutamic acid is an N-Boc-protected form of L-Glutamic acid (G596960). L-Glutamic acid is a nonessential amino acid that is important to the mammalian central nervous system. L-Glutamic acid is also a neurotransmitter for cone photoreceptors in the human brain and is used as a treatment for patients who have liver disease accompanied by encephalopathy (a condition termed ‘hepatic coma’).

Boc-L-Glutamic acid Preparation Products And Raw materials

Raw materials	Boc-L-glutamic acid 5-cyclohexyl ester-->Boc-L-glutamic acid 1-tert-butyl ester-->Boc-L-Glutamic acid 5-benzylester-->(S)-DIETHYL 2-(TERT-BUTOXYCARBONYLAMINO)PENTANEDIOATE(WX665212)-->(S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate-->Boc-L-Glutamic acid 1-benzyl ester-->BOC-GLU(OME)-OH-->Di-tert-butyl dicarbonate-->L-Glutamic acid
Preparation Products	(S)-Tert-Butyl (1,5-diaMino-1,5-dioxopentan-2-yl)carbaMate

Boc-Aib-OH Glutamic acid 1,1'-Carbonyldiimidazole Polyglutamic acid Ethyl 2-(Chlorosulfonyl)acetate Carbonyl iron powder Ascoric Acid Boc-L-Glutamic acid N-Carbobenzyloxyglycine L-Glutamic acid Folic acid tert-Butanol BOC-GLY-LEU-OH GLDH L-(+)Sodium glutamate L-Pyroglutamic acid tert-Butyl carbazate Citric acid

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Boc-L-Glutamic acid

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