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| | 1,1,1-Trifluoro-2,3-epoxypropane Basic information |
| Product Name: | 1,1,1-Trifluoro-2,3-epoxypropane | | Synonyms: | 3,3,3-Trifluoro-1,2-epoxypropane~2-(Trifluoromethyl)oxirane;1,2-EPOXY-3,3,3-TRIFLUOROPROPANE: TECH., 85%;1,1,1-TRIFLUORO-2,3-EPOXYPROPANE 98+%;1,2-EPOXY-3,3,3-TRIFLUOROPROPANE;1,1,1-TRIFLUORO-2,3-EPOXYPROPANE;2-(TRIFLUOROMETHYL)OXIRANE;3,3,3-TRIFLUORO-1,2-EPOXYPROPANE;3,3,3-Trifluoro-1,2-epoxypropane, tech | | CAS: | 359-41-1 | | MF: | C3H3F3O | | MW: | 112.05 | | EINECS: | 609-196-8 | | Product Categories: | organic chemical;Fluorochemicals | | Mol File: | 359-41-1.mol |  |
| | 1,1,1-Trifluoro-2,3-epoxypropane Chemical Properties |
| Boiling point | 38 °C | | density | 1,3 g/cm3 | | refractive index | 1.2997 | | Fp | -40°C | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | Specific Gravity | 1.3068 | | Water Solubility | Not miscible with water. | | Sensitive | Moisture Sensitive | | BRN | 103730 | | InChI | InChI=1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2 | | InChIKey | AQZRARFZZMGLHL-UHFFFAOYSA-N | | SMILES | O1CC1C(F)(F)F | | CAS DataBase Reference | 359-41-1(CAS DataBase Reference) | | NIST Chemistry Reference | 3,3,3-Trifluoro-1,2-epoxypropane(359-41-1) |
| | 1,1,1-Trifluoro-2,3-epoxypropane Usage And Synthesis |
| Uses | 1,2-Epoxy-3,3,3-trifluoropropane is used for the synthesis of trifluorolactic acid. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff. | | Synthesis | 31g of sodium hydroxide (3.28equiv.: 0.781mol)-water 60ml solution under ice-cooling, 50g bromohydrin form obtained in Example 6 (0.238mol) was added and the internal temperature was raised to 61 oC gas generated was collected outside the reactor, condensed in a trap cooled to -78 oC, 1,1,1-trifluoro-2 ,3-epoxypropane was obtained in 84% yield. This was analyzed by 1H-NMR, 19F-NMR. 19F-NMR: (acetone weight):-86.90ppm (3F, d) 1H-NMR: (acetone weight): 2.90ppm (1H, m) 2.96ppm (1H, d d), 3.40ppm (1H, m)
 | | Synthesis | To an autoclave (stainless steel, volume:1L) equipped with a mixing tank and a stirrer, C4F9I which compound (1) flow rate 25mL/min, CF2=CF2 (tetrafluoroethylene) which compound (2) flow rate 0.37g/min, (C2F5COO)2 (10 and half hour life temperature: 31°C) which compound (4) flow rate 0.052 mmol/min were supplied, the mixture was prepared by mixing at stirrer. Temperature in the autoclave was 10°C, residence time of the mixture in the autoclave was 10 minutes. The molar ratio (C4F9I/CF2=CF2)of C4F9I and CF2=CF2 in the mixed solution was 41, the amount of (C2F5COO)2 with respect to C4F9I was 0.034 mol%. Only the mixture from the bottom of the autoclave was withdrawn in the absence of gas phase, the mixture was fed to the bottom of tubular reactor (Tankan-shiki, volume: 0.5L). The mixture was not seperated by gas-liquid separation, the mixture was flow towards the outlet from the inlet of the reaction tube in the tube reactor. The temperature of the reaction tube, and a 70°C, the residence time of the mixture in the tubular reactor was set to 20 minutes. The mixture containing a compound (3) C6F13I was obtained.
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| | 1,1,1-Trifluoro-2,3-epoxypropane Preparation Products And Raw materials |
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