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| | (1R)-(+)-ALPHA-PINENE Basic information |
| | (1R)-(+)-ALPHA-PINENE Chemical Properties |
| Melting point | −62 °C(lit.) | | Boiling point | 155-156 °C(lit.) | | density | 0.858 g/mL at 20 °C(lit.) | | vapor pressure | 5 hPa (25 °C) | | refractive index | n20/D 1.465(lit.) | | FEMA | 2902 | ALPHA-PINENE | | Fp | 91 °F | | storage temp. | Store at +2°C to +8°C. | | form | Liquid | | color | Clear colorless | | Odor | at 10.00 % in dipropylene glycol. harsh terpene aromatic minty | | Odor Type | herbal | | optical activity | [α]22/D +47.1°, neat | | explosive limit | 0.8-6%(V) | | Water Solubility | Soluble in Ether, Alcohols, Chloroform. Not miscible in water. | | Merck | 14,7445 | | JECFA Number | 1329 | | BRN | 3648264 | | InChIKey | GRWFGVWFFZKLTI-UHFFFAOYSA-N | | LogP | 4.44-4.46 at 20-37℃ | | CAS DataBase Reference | 7785-70-8(CAS DataBase Reference) | | EPA Substance Registry System | Bicyclo[3.1.1]hept-2-ene, 2,6,6-trimethyl-, (1R,5R)- (7785-70-8) |
| Hazard Codes | Xi | | Risk Statements | 10-36/37/38 | | Safety Statements | 26-36-16-23 | | RIDADR | UN 2368 3/PG 3 | | WGK Germany | 3 | | RTECS | DT7000000 | | F | 10 | | Autoignition Temperature | 491 °F | | TSCA | Yes | | HS Code | 2902 19 00 | | HazardClass | 3 | | PackingGroup | III |
| | (1R)-(+)-ALPHA-PINENE Usage And Synthesis |
| Chemical Properties | (1R)-(+)-ALPHA-PINENE is Clear colourless liquid
| | Uses | (1R)-(+)-α-Pinene is used in hydroboration reactions and the reduction of ketones. | | Uses | (+)-alpha-Pinene is employed in the preparation of chiral hydroboration reagents. It is a bronchodilator in humans. α-Pinene is an anti-inflammatory and used as a broad-spectrum antibiotic.It exhibits activity as an acetylcholinesterase inhibitor, aiding memory. It is a biosynthetic base for CB2 ligands, such as HU-308. | | Uses | (+)-α-Pinene has been used in a tolerance testing procedure to detect the genes in Marinobacter aquaeolei, for engineering a pinene tolerant Escherichia coli. | | Definition | ChEBI: The (+)-enantiomer of alpha-pinene. | | General Description | (+)-α-Pinene is a monoterpenoid compound mainly found in Pinus species. | | Flammability and Explosibility | Flammable | | Purification Methods | (1R)-(+)-ALPHA-PINENE is isomerised by heat, acids and certain solvents. It should be distilled under reduced pressure under nitrogen and stored in the dark. It has been purified via the nitrosochloride [Waterman et al. Recl Trav Chim, Pays-Bas 48 1191 1929]. For purification of optically active forms see Lynn [J Am Chem Soc 91 361 1919].
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| | (1R)-(+)-ALPHA-PINENE Preparation Products And Raw materials |
| Raw materials | Bicyclo[3.1.1]hept-2-ene, 6,6-dimethyl-4-methylene-, (1S,5S)--->Borane, dichloro[(1R,2S,3R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]--->(S)-1-PHENYL-BUT-3-EN-1-OL-->2-Cyclohexene-1-methanol, α-methyl-, (αR,1R)--->[1R-(1alpha,2beta,5alpha)]-2,6,6-trimethylbicyclo[3.1.1]heptan-3-one-->[(1R,2S,3R,5R)-2,6,6-Trimethylbicyclo[3.1.1]hept-3-yl]borane-->(-)-Diisopinocampheyl borane | | Preparation Products | (1S,2S,3R,5S)-(+)-2,3-Pinanediol-->2,6-DIMETHYL-2,4,6-OCTATRIENE-->p-Cymene-->(1R)-(+)-CIS-PINANE-->cis-4-hydroxy-alpha,alpha,4-trimethylcyclohexanemethanol-->(-)-ISOPINOCAMPHEYLAMINE-->(1S,2S,5S)-(-)-2-Hydroxy-3-pinanone |
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