1-Boc-pyrazole-4-boronic acid pinacol ester

1-Boc-pyrazole-4-boronic acid pinacol ester Basic information

Product Name:	1-Boc-pyrazole-4-boronic acid pinacol ester
Synonyms:	1-Boc-4-pyrazoleboronic acid pinacol ester, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-Boc-pyrazole, tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-pyrazolecarboxylate;TERT-BUTYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE CARBOX., 97%;1-tert-Butoxycarbonyl-4-1H-pyrazoleboronic acid;4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylic acid tert-butyl e;1-BOC-PYRAZOLE-4-BORONIC ACID PINACOL ESTER, 97%;1-TERT-BUTOXYCARBONYL-4-1H-PYRAZOLBORONIC ACID PINACOL ESTER;N-Boc-pyrazole-4-boronic acid pinaxcol ester;1-BOC- 4-PYRAZOLEBORONIC ACID PINACOL ESTER
CAS:	552846-17-0
MF:	C14H23BN2O4
MW:	294.15
EINECS:
Product Categories:	Boric Acid\| Boric Acid Ester\| Potassium Trifluoroborate
Mol File:	552846-17-0.mol

1-Boc-pyrazole-4-boronic acid pinacol ester Chemical Properties

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

1-Boc-pyrazole-4-boronic acid pinacol ester Usage And Synthesis

Chemical Properties	white to beige crystalline powder
Uses	1-Boc-pyrazole-4-boronic Acid Pinacol Ester is used as a reagent in the synthesis of several inhibitors including thieno[3,2-c]pyridin-4-amines which are a novel series of Bruton’s tyrosine kinase (BTK) inhibitors which can be used in drug design.

1-Boc-pyrazole-4-boronic acid pinacol ester Preparation Products And Raw materials

Raw materials	tert-Butyl 4-iodopyrazole-1-carboxylate-->1-Boc-4-bromopyrazole-->tert-Butyl 1H-pyrazole-1-carboxylate-->Di-tert-butyl dicarbonate-->4-Pyrazoleboronic acid pinacol ester-->Pinacolborane-->Bis(pinacolato)diboron
Preparation Products	LMI070-->1H-Pyrazole-1-carboxylic acid, 4-(3-bromophenyl)-, 1,1-dimethylethyl ester-->1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)--->Pyrido[2,3-d]pyrimidin-7(8H)-one, 2-amino-8-cyclopentyl-4-methyl-6-(1H-pyrazol-4-yl)-

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