(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Basic information
Product Name:(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms:(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one;Ezetimibe Impurity J;Ezetimibe Impurity L;Ezetimibe impuriry 12/N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe/(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one;Ezetimibe-10;(3R,4S)-1-(4-chlorophenyl);2-Azetidinone, 1-(4-chlorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-;1-(4-Chloropheneyl)ezetimibe
CAS:1700622-08-7
MF:C24H21ClFNO3
MW:425.88
EINECS:
Product Categories:
Mol File:1700622-08-7.mol
(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Structure
(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties
Boiling point 676.0±55.0 °C(Predicted)
density 1.354±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka9.72±0.30(Predicted)
color White to Off-White
Safety Information
MSDS Information
(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Usage And Synthesis
UsesN-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe is a derivative of Ezetimibe (E975000), which is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.
(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Preparation Products And Raw materials
ent-EzetiMibe (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one EzetiMibe ring-opening dehydrate iMpurity ent-Ezetimibe Ketone Ezetimibe-13C6 Ulipristal Acetate EzetiMibe Dehydoxy IMpurity 4-Benzyloxybenzaldehyde (S)-(+)-4-Phenyl-2-oxazolidinone (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impurity 55 Ezetimibe Benzyl Impurity (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one Ezetimibe Related Impurity 7 4-Fluoroaniline (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One EZETIMIBE HYDROXY GLUCURONIDE

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