tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate Basic information
Product Name:tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
Synonyms:tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate;6-Hydroxymethyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester;2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-6-(hydroxymethyl)-, 1,1-dimethylethyl ester;tert-butyl 6-(hydroxymethyl)-3,4-dihydro-1H-isoquinoline-2-carboxylate
CAS:622867-52-1
MF:C15H21NO3
MW:263.33
EINECS:
Product Categories:
Mol File:622867-52-1.mol
tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure
tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate Chemical Properties
Boiling point 403.7±45.0 °C(Predicted)
density 1.153±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka14.44±0.10(Predicted)
Safety Information
MSDS Information
tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate Usage And Synthesis
UsesN-Boc-6-hydroxymethyl-1,2,3,4-tetrahydroisoquinoline is an intermediate used to prepare phosphonate-substituted HIV protease inhibitors for treatment of AIDS and other viral infections. It is also used in the synthesis of immunosuppressant heterocyclic compdounds for treating or preventing diseases assocd. with EDG receptor mediated signal transduction.
tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate Preparation Products And Raw materials

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