|
| | Xanthone Basic information |
| | Xanthone Chemical Properties |
| Melting point | 172-174 °C(lit.) | | Boiling point | 349-350 °C730 mm Hg(lit.) | | density | 1.1607 (rough estimate) | | refractive index | 1.6000 (estimate) | | Fp | 350-351°C | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly, Heated) | | form | neat | | color | White to Light Purple | | Water Solubility | It is Soluble in water (partly), chloroform, hot Toluene, ether (slightly), and hot alcohol. | | Merck | 14,10062 | | BRN | 140443 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChIKey | JNELGWHKGNBSMD-UHFFFAOYSA-N | | CAS DataBase Reference | 90-47-1(CAS DataBase Reference) | | NIST Chemistry Reference | Xanthone(90-47-1) | | EPA Substance Registry System | 9H-Xanthen-9-one (90-47-1) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22 | | Safety Statements | 24/25-62-45 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | ZD5711000 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29329990 |
| | Xanthone Usage And Synthesis |
| Description | Xanthone is a compound that has been shown to have a significant cytotoxicity against HL-60 cells and to inhibit the cyclase enzyme. It also inhibits the protein production of mcl-1, which is necessary for the development of cancer cells. | | Chemical Properties | off-white powder | | Uses | Xanthone is used predominantly as oxygenated polycyclic aromatic compounds, and as a vasorelaxant. It can be used as a fluorescent agent, as well as an intermediate in organic synthesis and chemical research. | | Uses | Acts as an inhibitor of human cancer cell lines. | | Definition | A colorless crystalline organic compound found as a pigment in
gentians and other flowers. It is used as an
insecticide and in making dyestuffs. | | Application | Xanthone has antiinflammatory activity and can be used in treating infectious diseases such as tuberculosis, malaria, and leprosy. The biological properties of it are shown by its ability to scavenge anion radicals and to act as a fluorescence probe for coumarin derivatives. | | Definition | ChEBI: The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 37, p. 4204, 1972 DOI: 10.1021/jo00798a059 | | Purification Methods | It has also been recrystallised from n-hexane three times and sublimed in vacuo. [Saltiel J Am Chem Soc 108 2674 1986]. [Beilstein 17 H 354, 17 I 190, 17 II 378, 17 III/IV 5292, 17/10 V 430.] |
| | Xanthone Preparation Products And Raw materials |
|
