AFLATOXIN G2

AFLATOXIN G2 Basic information
Product Name:AFLATOXIN G2
Synonyms:)pyrano(3,4-c)(1)-benzopyran-1,12-dione;10a-hexahydro-5-methoxy-1(7ar-cis)-;12h-furo(3’,2’:4,5)furo(2,3-h)pyrano(3,4-c)(1)benzopyran-1,12-dione,3,4,7a-1;(7aR,cis)3,4,7a,9,10,10a-hexahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione;AF G2;AFLATOXIN G2(RG);(7aR)-3,4,7aα,9,10,10aα-Hexahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione;3,4,7aα,9,10,10aα-Hexahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione
CAS:7241-98-7
MF:C17H14O7
MW:330.29
EINECS:230-643-4
Product Categories:antibiotic;CRM&Matrix RMApplication CRMs;CarcinogensCell Signaling and Neuroscience;Cancer Research;Food and Agriculture CRM;Other;Mold;Toxins and Venoms;A;AA to ALBiotoxins;Alphabetic;Mycotoxins;Single component solutions;Biotoxins;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:7241-98-7.mol
AFLATOXIN G2 Structure
AFLATOXIN G2 Chemical Properties
Melting point 237-240 °C
alpha D -473° (c = 0.084 in chloroform)
Boiling point 387.74°C (rough estimate)
density 1.3099 (rough estimate)
refractive index 1.4790 (estimate)
Fp 2 °C
storage temp. 2-8°C
solubility DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form White to yellow powder. Blue-green fluorescence.
Water Solubility 15mg/L(temperature not stated)
BRN 1692017
LogP0.443 (est)
EPA Substance Registry SystemAflatoxin G2 (7241-98-7)
Safety Information
Hazard Codes T+,T,Xn,F
Risk Statements 45-26/27/28-36-20/21/22-11-39/23/24/25-23/24/25-65-48/23/24/25-36/38-46
Safety Statements 53-28-36/37-45-36-26-16-7-62
RIDADR UN 3462 6.1/PG 1
WGK Germany 3
RTECS LV1700000
HazardClass 6.1(a)
PackingGroup I
HS Code 30029090
Hazardous Substances Data7241-98-7(Hazardous Substances Data)
ToxicityLD50 orally in day old duckling: 172.5 mg/50 gm body wt (Carnaghan)
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
AFLATOXIN G2 Usage And Synthesis
Chemical Propertiesyellow powder
Chemical PropertiesThe aflatoxins are a group of molds produced by the fungus Aspergillus flavus. They are natural contaminants of fruits, vegetables, and grains. They are also described as a series of condensed ring heterocyclic compounds. They form colorless to pale yellow crystals. Practically insoluble in water.
UsesAflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects.
UsesAflatoxin G2 is the minor analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed.
DefinitionChEBI: Aflatoxin G2 is a member of coumarins.
General DescriptionVery light and fluffy crystalline solid. Exhibits green-blue fluorescence.
Air & Water ReactionsSlightly water soluble
Reactivity ProfileAFLATOXIN G2 is incompatible with strong oxidizing agents, strong acids and strong bases.
Health HazardACUTE/CHRONIC HAZARDS: AFLATOXIN G2 is extremely toxic. Ingestion of even microgram quantities can cause toxic affects and, possibly, death. It can also be absorbed through the skin. Allow only your most experienced personnel to work with AFLATOXIN G2. All non-essential personnel should leave the laboratory.
Fire HazardFlash point data for AFLATOXIN G2 are not available. AFLATOXIN G2 is probably combustible.
Biochem/physiol ActionsHepatocarcinogen. Food contaminant produced by Aspergillus flavus, a common soil fungus.
Potential ExposureAflatoxins are a group of toxic metabolites produced by certain types of fungi. Aflatoxins are not commercially manufactured; they are naturally occurring contaminants that are formed by fungi on food during conditions of high temperatures and high humidity. Most human exposure to aflatoxins occurs through ingestion of contaminated food. The estimated amount of aflatoxins that Americans consume daily is estimated to be 0.15 0.50 μg. Grains, peanuts, tree nuts, and cottonseed meal are among the more common foods on which these fungi grow. Meat, eggs, milk, and other edible products from animals that consume aflatoxincontaminated feed may also contain aflatoxins. Aflatoxins can also be breathed in
ShippingUN3172 Toxins, extracted from living sources, solid or liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Use of oxidizing agents, such as hydrogen peroxide or 5% sodium hypochlorite bleach. Acids and bases may also be used.
AFLATOXIN G2 Preparation Products And Raw materials
3-Methylphenethyl alcohol 3,5-DIPROPOXYPHENOL trans-2,3-Dimethoxycinnamic acid 3-Phenoxypropionic acid ETHYL PHENYL MALONATE AFLATOXIN G2 5,6-DIHYDRO-2H-PYRAN-3-CARBOXYLIC ACID 7-HYDROXY-3,4,8-TRIMETHYLCOUMARIN 3-(4-BUTOXYPHENYL)-2-PROPENOIC ACID 7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID METHYL ESTER 2H-CHROMENE-3-CARBOXYLIC ACID 3,4-DIMETHYL-CHROMEN-2-ONE 4-Methoxycinnamic acid 2-(4-methoxy-3-methylphenyl)ethanol 2-METHOXYHYDROCINNAMIC ACID (2E)-3-(2,3-DIHYDROBENZOFURAN-5-YL)PROPENOICACID 7-METHOXY-2H-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER 5,6-dihydro-2H-pyran-3-carbaldehyde

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