N-(1-PYRENYL)MALEIMIDE

N-(1-PYRENYL)MALEIMIDE Basic information

Product Name:	N-(1-PYRENYL)MALEIMIDE
Synonyms:	1-(1-Pyrenyl)-1H-pyrrole-2,5-dione;1-(1-Pyrenyl)-3-pyrroline-2,5-dione;N-(Pyren-1-yl)maleimide;Pyrene maleimide;N-(1-Pyrenyl)maleimide,99%;N-[3-PYRENYL]MALEIMIDE;N-(1-PYRENE)MALEIMIDE;N-(1-PYRENYL)MALEIMIDE
CAS:	42189-56-0
MF:	C20H11NO2
MW:	297.31
EINECS:	255-702-1
Product Categories:	Biochemicals and Reagents;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Cyclic Imides;Derivatization agents;Luminescent Compounds/Detection;Organic Building Blocks;Fluorescent Labels and Indicators;Analytical Chemistry;Fluorescence Detection (HPLC Labeling Reagents);HPLC Labeling Reagents;Mercapto Group Labeling Reagents for Fluorescence HPLC;N-Substituted Maleimides;N-Substituted Maleimides, Succinimides & Phthalimides;Pyrenes;Fluorescent Labels & Indicators;Maleimide Derivatives;MTS & Sulfhydryl Active Reagents;Cyclic ImidesBiochemicals and Reagents;Carbonyl Compounds;Derivatization agents;Luminescent Compounds/Detection;Organic Building Blocks
Mol File:	42189-56-0.mol

N-(1-PYRENYL)MALEIMIDE Chemical Properties

Melting point	235-237 °C(lit.)
Boiling point	438.82°C (rough estimate)
density	1.2310 (rough estimate)
refractive index	1.5180 (estimate)
storage temp.	Refrigerator
solubility	Soluble in chloroform, N,Ndimethylformamide, dimethyl sulfoxide, ethanol, methanol
pka	–1.21±0.20, most basic, temperature: 25°C
form	Solid
color	Yellow needles;Gold needles
λmax	338nm, 325nm (MeOH)
BRN	1542661
Major Application	Dendrimers; dye functionalized single-wall carbon nanotube (SWNT) conjugated polymer devices; photovoltaic cells; polymer-coated gold electrodes; fluorescent polymers; radio-fluorogenic gel; in sequencecontrolled polymerizations; rubber
Biological Applications	Analyzing molecular aspects of muscle contraction; detecting nucleic acids, proteins; determining/evaluating cell activity; diagnosing/treating Parkinson’s disease; monitoring/studying ribosomal structure and conformation; studying nicotinic acetylcholine receptor (AChR) structure; sulfhydryl reagent
CAS DataBase Reference	42189-56-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	1
F	8-10-21
HS Code	29251900

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

N-(1-PYRENYL)MALEIMIDE Usage And Synthesis

Chemical Properties	N-(1-PYRENYL)MALEIMIDE is Yellow Solid
Uses	N-(1-PYRENYL)MALEIMIDE is a fluorescent sulfhydryl reagent that can form excited-state dimers which emit at longer wavelenghts than the lone excited fluorophore.
Uses	Reactant used in synthesis of: • ;Oligodeoxynucleotide derivatives1 • ;Polymer conjugates of immunogenic peptides2 • ;Modified oligonucleotides for biosensing applications3,Reactant: • ;Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers4• ;Used as derivitizing agent for determination of glutathione disulfide levels in biological samples5

N-(1-PYRENYL)MALEIMIDE Preparation Products And Raw materials

N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA (S)-(-)-N-(1-PHENYLETHYL)MALEIMIDE Mal-PEG4-NHS ester Mal-PEG6-Acid N-Succinimidyl S-Acetylthioglycolate N-BENZYL-2 3-DIBROMOMALEIMIDE 97 N,N-Dimethyl-1-naphthylamine 1-Aminopyrene 1-(2-NAPHTHALENYL)-1H-PYRROLE-2,5-DIONE N-(1-PYRENYL)MALEIMIDE N,N-DIMETHYL-2-NAPHTHYLAMINE Pyrene N-Ethyl-1-naphthylamine N,N-DIETHYL-1-NAPHTHYLAMINE N-(1-NAPHTHYL) ACRYLAMIDE Maleimide 1-AMINOPHENANTHRENE 1-NAPHTHALEN-1-YL-PYRROLE-2,5-DIONE

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