Ticabesone Propionate

Ticabesone Propionate Basic information
Product Name:Ticabesone Propionate
Synonyms:Androsta-1,4-diene-17- carbothioic acid,6,9-difluoro-11- hydroxy-16-Methyl-3-oxo-17-(1- oxopropoxy)-, S-Methyl ester, (6α,11β,16α,17α)-;6α,9-Difluoro-17-[(methylsulfanyl)carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yle propanoate;Fluticasone Methylsulphanyl Analog;Ticabesone Propionate;Fluticasone Propionate EP Impurity D;Fluticasone Propionate EP Impurity D/Fluticasone Methylsulphanyl Analog/Ticabesone Propionate/6α,9-Difluoro-17-[(methylsulphanyl)carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-ylpropanoate;Fluticasone EP Imp D;(6alpha,8xi,10xi,11beta,14xi,16alpha,17alpha)-6,9-difluoro-11-hydroxy-16-methyl-17-[(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propanoate
CAS:73205-13-7
MF:C25H32F2O5S
MW:482.58
EINECS:
Product Categories:
Mol File:73205-13-7.mol
Ticabesone Propionate Structure
Ticabesone Propionate Chemical Properties
Melting point 266 - 268°C
Boiling point 569.4±50.0 °C(Predicted)
density 1.29±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly)
pka12.56±0.70(Predicted)
form neat
color White to Off-White
InChIKeyDRXCUKXWTNOXTD-CENSZEJFSA-N
Safety Information
HS Code 2937220000
MSDS Information
Ticabesone Propionate Usage And Synthesis
UsesTicabesone Propionate is an impurity of Fluticasone, an antiallergic, anti-asthmatic and anti-inflammatory agent.
Brand nameTicabesone is INN.
Ticabesone Propionate Preparation Products And Raw materials
Fluticasone propionate-d5 Fluticasone propionate (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)- DesfluoroMethyl Fluticasone Propionate Disulfide (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid Fluticasone Acetate FLUTICASONE FUROATE 5-Iodomethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate Fluticasone EP IMpurity B Fluticasone (6α,11β,16α,17α)-(6'α,11'β,16'α,17'α)-17,17'-(Trithiodicarbonyl)bis[6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-androsta-1,4-dien-3-one Fluticasone FLUTICASONE PROPIONATE, 17-BETA CARBOXYLIC ACID (6α,11β,16α,17α)-6,9-difluoro-11,17-dihydroxy-16-Methyl-3-oxo-Androsta-1,4-diene-17-carboxylic Acid (6α,11β,16α,17α)-6,9-difluoro-17-[[(fluoroMethyl)thio]carbonyl]-11-hydroxy-16-Methyl-3-oxoandrosta-1,4-dien-17-yl Ester 5-Chloromethyl 6a,9a-Difluoro-11-hydroxy-16a-methyl-3-oxo-17a-(propionyloxy)-androsta-1,4-diene-17-carbothioate 11-Oxo Fluticasone Propionate (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-Methyl-spiro[androsta-1,4-diene-17,5'-[1,3]oxathiolane]-2',3,4'-trione Fluticasone

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