Dasatinib DiMeric IMpurity

Dasatinib DiMeric IMpurity Basic information
Product Name:Dasatinib DiMeric IMpurity
Synonyms:Dasatinib DiMeric IMpurity;Dasatinib Impurity 8 (Dasatinib Dimeric Impurity);2,2'-[1,4-Piperazinediylbis[(2-methyl-6,4-pyrimidinediyl)imino]]bis[N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide;Dasatinib Dimer Impurity;Dasatinib impurity 6/Dasatinib Dimeric Impurity/2,2'-((piperazine-1,4-diylbis(2-methylpyrimidine-6,4-diyl))bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide);dasatinib Dimer IMP;N-(2-chloro-6-methylphenyl);5-Thiazolecarboxamide, 2,2'-[1,4-piperazinediylbis[(2-methyl-6,4-pyrimidinediyl)imino]]bis[N-(2-chloro-6-methylphenyl)- (9CI)
CAS:910297-61-9
MF:C36H34Cl2N12O2S2
MW:801.77
EINECS:
Product Categories:Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors
Mol File:910297-61-9.mol
Dasatinib DiMeric IMpurity Structure
Dasatinib DiMeric IMpurity Chemical Properties
density 1.501±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Very Slightly)
form Solid
pka10?+-.0.70(Predicted)
color Off-White to Dark Beige
Safety Information
MSDS Information
Dasatinib DiMeric IMpurity Usage And Synthesis
UsesDasatinib Dimeric Impurity, is an impurity of Dasatinib (D193600), which is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. It is also an Antineoplastic. It is a COVID19-related research product.
Dasatinib DiMeric IMpurity Preparation Products And Raw materials
Hydroxymethyl Dasatinib N-Deshydroxyethyl Dasatinib Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Dasatinib Impurity 24 Dasatinib Carboxylic Acid 2-(4-(6-((5-((2-chloro-6-Methylphenyl)carbaMoyl)thiazol-2-yl)aMino)-2-MethylpyriMidin-4-yl)piperazin-1-yl)ethyl acetate N-Deshydroxyethyl Dasatinib-d8 2’-Deschloro-2’-hydroxy Dasatinib Dasatinib N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide Dasatinib N-Oxide 4-[6-[[5-[[(2-Chloro-6-Methylphenyl)aMino]carbonyl]-2-thiazolyl]aMino]-2-Methyl-4-pyriMidinyl]-1-piperazineacetic Acid Ethyl Ester Dasatinib-d8 Dasatinib iMpurity (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide 5-Thiazolecarboxylic acid,2-[(6-chloro-2-Methyl-4-pyriMidinyl)aMino]-

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