N-Boc-L-trans-4,5-Methanoproline

N-Boc-L-trans-4,5-Methanoproline Basic information
Uses
Product Name:N-Boc-L-trans-4,5-Methanoproline
Synonyms:N-Boc-L-trans-4,5-Methanoproline;(1R,3S,5R)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxyl+;N-Boc-L-trans-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) ester, (1R,3S,5R)-;EOS-61213;(1R,3S,5R)-2-(tert-butoxyCARBONYL)-2-AZABICLO[3.1.0]hexane-3-carboxylic acid;(1R,3S,5R)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid;N-tert-butoxycarbonyl-l-trans-2-azabicyclo 3.1.0 hexane-3-carboxylic acid
CAS:197142-34-0
MF:C11H17NO4
MW:227.26
EINECS:815-186-6
Product Categories:
Mol File:197142-34-0.mol
N-Boc-L-trans-4,5-Methanoproline Structure
N-Boc-L-trans-4,5-Methanoproline Chemical Properties
Boiling point 355.9±25.0 °C(Predicted)
density 1.276±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Acetone (Slightly, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly, Heated)
pka4.03±0.20(Predicted)
form Solid
color White to Pale Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
N-Boc-L-trans-4,5-Methanoproline Usage And Synthesis
UsesN-Boc-L-trans-4,5-Methanoproline belongs to carboxylic acid derivatives and can be used as pharmaceutical intermediates.
Uses1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid acts as a reagent in the preparation of fused bicycles end-capped with peptide derivatives as HCV inhibitors. Synthesis of (tert-butoxycarbonyl)azabicyclohexanecarboxylic acid via stereoselective cyclopropanation of pyrroline
N-Boc-L-trans-4,5-Methanoproline Preparation Products And Raw materials
Preparation Productstert-butyl (3S)-3-(hydroxymethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate-->(1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID
1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-diMethylethyl) 2-ethyl ester, (2S)- [15N,2H2]-Saxagliptin Hydrochloride AcetaMide, N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-2,2,2-trifluoro- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)- DSLXQSYLYSTVKT-ONZQNKQFSA-N (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID (2R)-1,2-Pyrrolidinedicarboxylic acid 1-tert-butyl 2-ethyl ester 2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) 3-ethyl ester, (1S,3S,5S)- (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic acid ethyl ester (S) - N- Boc- adamantylglycine 1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)- Saxagliptin hydrochloride 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-tricyclo[3.3.1.13,7]dec-1-ylacetyl]-, (1S,3S,5S)- 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3R,5R)- (1S,3R,5S)-2-tert-Butyl 3-ethyl 2-azabicyclo[3.1.0]hexane-2,3-dicarboxylate (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXAMIDE 2,2,2-TRIFLUOROACETIC ACID BOC-DL-PROLINE ETHYL ESTER 1-tert-butyl 2-ethyl 2,3-dihydro-1H-pyrrole-1,2-dicarboxylate

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