24R-Calcipotriol

24R-Calcipotriol Basic information
Product Name:24R-Calcipotriol
Synonyms:24R-Calcipotriol;IMpurity D of Calcipotriol;PRI 2202;(24R)-Calcipotriene;(1alpha,3beta,5Z,7E,22E,24R)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol;Impurity D of Calcipotriol (PRI 2202);5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4R)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol;Calcipotriol impurity D
CAS:112827-99-3
MF:C27H40O3
MW:412.6
EINECS:
Product Categories:Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:112827-99-3.mol
24R-Calcipotriol Structure
24R-Calcipotriol Chemical Properties
Boiling point 582.0±50.0 °C(Predicted)
density 1.12±0.1 g/cm3(Predicted)
storage temp. -20°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
solubility Chloroform (Slightly), Methanol (Slightly)
pka14.29±0.20(Predicted)
form Powder
Stability:Light sensitive, Temperature sensitive
Safety Information
MSDS Information
24R-Calcipotriol Usage And Synthesis
Uses(24R)-Calcipotriene is a synthetic analogs of vitamin D that was studied for its potential antitumor effects. Studies has shown the combined treatment with vitamin D analog (24R)-Calcipotriene was more effective than the treatment with cytostatics applied alone. (24R)-Calcipotriene is also the 24-R epimer of Calcipotriene (C144200).
24R-Calcipotriol Preparation Products And Raw materials
Raw materialsCalcipotriene
(1S,4R,E)-4-((1R,3aS,7aR,E)-4-((Z)-2-((3S,5R)-3,5-bis((tert-butyldiMethylsilyl)oxy)-2-Methylenecyclohexylidene)ethylidene)-7a-Methyloctahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-ol Calcipotriene (5Z,7E,22E)-9,10-Seco-26,27-cyclo-1α,3β-dihydroxycholesta-5,7,10(19),22-tetren-24-one

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