ClotriMazole IMpurity A

ClotriMazole IMpurity A Basic information

Product Name:	ClotriMazole IMpurity A
Synonyms:	1-(p-Chloro-α,α-diphenylbenzyl)iMidazole;1-[(4-Chlorophenyl)diphenylMethyl]-1H-iMidazole;1-[(p-Chlorophenyl)diphenylMethyl]iMidazole;CDD 3532;para-ClotriMazole IsoMer;ClotriMazole IMpurity B;Clotrimazole-001;Clotrimazole EP Impurity B
CAS:	23593-71-7
MF:	C22H17ClN2
MW:	344.84
EINECS:
Product Categories:
Mol File:	23593-71-7.mol

ClotriMazole IMpurity A Chemical Properties

Melting point	138-140°C
Boiling point	475.9±40.0 °C(Predicted)
density	1.13±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka	6.28±0.30(Predicted)
form	Solid
color	White to Off-White

Safety Information

MSDS Information

ClotriMazole IMpurity A Usage And Synthesis

Uses	para-Clotrimazole Isomer is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rode nts.
Uses	para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.

ClotriMazole IMpurity A Preparation Products And Raw materials

Raw materials

4-Chlorophenyl-diphenylmethyl Chloride-->Benzenemethanol,4-chloro-a,a-diphenyl--->Imidazole

2-Chlorobenzotrichloride 1-(Triphenylmethyl)imidazole 1-Chloro-2-(dichlorophenylMethyl)benzene Benzenemethanol,4-chloro-a,a-diphenyl- TRAM-34 ETHYLTRITYLETHER (2-Chlorophenyl)phenyl-methanone CLOTRIMAZOLE IMP. A (PHARMEUROPA): (2-CHLOROPHENYL)DIPHENYLMETHANOL (2-CHLOROPHENYL)DIPHENYLMETHANE ClotriMazole IMpurity B Imidazole Clotrimazole 2-Chlorotrityl chloride

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