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Quinine sulfate dihydrate

Quinine sulfate dihydrate Basic information
Product Name:Quinine sulfate dihydrate
Synonyms:Quinine sulfate fluorescence standard substance;QUININE SULPHATE 2H2O;Quinine sulfate hydrate(2:1:4);CHININI SULFAS;(-)-QUININE SULFATE DIHYDRATE;QUININE SULFATE DIHYDRATE;QUININE SULPHATE DIHYDRATE;Quinine monohydrate hemisulfate salt
CAS:6119-70-6
MF:C20H26N2O6S
MW:422.5
EINECS:639-128-2
Product Categories:API;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Herb extract;Antiparasitic / Antiprotozoal / AnthelminthicBiochemicals and Reagents;AlkaloidAntibiotics;Antibiotics A to;Antibiotics N-SAntibiotics;Biochemicals Found in Plants;Detection;Fluorescent Probes, Labels, Particles and Stains;Nutrition Research;Spectrum of Activity;Antiparasitic / Antiprotozoal / AnthelminthicVoltage-gated Ion Channels;Monovalent Ion Channels;Potassium Channel Modulators;6119-70-6
Mol File:6119-70-6.mol
Quinine sulfate dihydrate Structure
Quinine sulfate dihydrate Chemical Properties
Melting point ~225 °C (dec.)(lit.)
alpha -245 º (c=2, 0.1M HCl)
FEMA 2977 | QUININE SULFATE
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Soluble in a mixture of chloroform and absolute alcohol (2:1).
form Crystalline Powder
color Light yellow or beige to brown
Odorodorless
Odor Typeodorless
Water Solubility 0.12 g/100 mL (20 ºC)
Sensitive Light Sensitive
Merck 14,8061
BRN 6113937
Stability:Stable. Incompatible with strong oxidizing agents, alkalies, ammonia, strong bases, iodine.
InChIKeyAKYHKWQPZHDOBW-QJLYHTAINA-N
SMILES[C@H]([C@]1([H])C[C@@H]2CC[N@]1C[C@@H]2C=C)(C1=CC=NC2=CC=C(OC)C=C12)O.S(O)(O)(=O)=O |&1:0,1,4,7,9,r|
LogP3.44
CAS DataBase Reference6119-70-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-42/43-22-36/38
Safety Statements 26-45-37-24-37/39
RIDADR UN 2811
WGK Germany 3
RTECS VA8440000
F 8
TSCA Yes
HS Code 29392000
MSDS Information
ProviderLanguage
ACROS English
ALFA English
Quinine sulfate dihydrate Usage And Synthesis
Chemical PropertiesQuinine sulfate is odorless and has a persistent, very bitter taste. It darkens on exposure to light. Its saturated solution is neutral or alkaline to litmus.
Chemical PropertiesWhite or almost white, crystalline powder or fine, colourless needles.
UsesPrimary alkaloid of various species of Cinchona (Rubiaceae). Optical isomer of Quinidine. Antimalarial; muscle relaxant (skeletal).
UsesQuinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
UsesQuinine sulfate is an antimalarial agent also used as antipyreticum and in liquids (tonic etc.).
Brand nameCoco-Quinine (Lilly).
SynthesisManufacture of quinine by extraction from cinchona bark and subsequent purification and synthesis to quinine sulfate
Quinine sulfate dihydrate Preparation Products And Raw materials
QUININE SULFATE, FLUORESCENCE QUININE SULFATE USP(CRM STANDARD) Viqualine Vanadyl sulfate QUININE SULFATE SALT CINCHONIDINE SULFATE Quinine sulfate *Fluorescence Reference Standard QUININE SULFATE n-Dodecyl alcohol, sulfated (1S,2S,5S)-2-(HYDROXYMETHYL)-5-VINYLQUINUCLIDINE QUININE SULFATE QUININE SULFATE SALT MONOHYDRATE quinine,sulfate(1:1)(salt),heptahydrat QUININE SULFATE,Quinine, sulfate (2:1) (salt) (8CI) GOLD COAST SOLUTION NO 1 Cinchona ledgeriana bark FOROXYMITHINE Quinine sulfate dihudrate Quinine Sulphate Dihydrate
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