Bis[(2-guanidino-4-thiazolyl)methyl]disulfide

Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Basic information
Product Name:Bis[(2-guanidino-4-thiazolyl)methyl]disulfide
Synonyms:Bis[(2-guanidino-4-thiazolyl)methyl]disulfide;Bis[(2-guanidino-4-thiazolyl)Methyl]disulfide (FaMotidine IMpurity);Famotidine Related Compound E (25 mg) (2,2'-[4,4'-disulfanediylbis(methylene)bis(thiazole-4,2-diyl)]diguanidine);N,N'''-[Dithiobis(Methylene-4,2-thiazolediyl)]bisguanidine;Bis[(2-guanidino-4-thiazolyl)Methyl]disulfide (85%) (FaMotidine IMpurity);FaMotidine Related CoMpound E;Famotidine EP Impurity E (USP RC E);2,2'-[Disulfanediylbis-(methyleneth
CAS:129083-44-9
MF:C10H14N8S4
MW:374.53
EINECS:
Product Categories:Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds;Sulfur & Selenium Compounds;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:129083-44-9.mol
Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Structure
Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Chemical Properties
Melting point 155-157°C
Boiling point 601.0±65.0 °C(Predicted)
density 1.86±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility DMF (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka8.77±0.70(Predicted)
color Off-White to Pale Beige
Safety Information
HS Code 2934990002
MSDS Information
Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Usage And Synthesis
UsesA potential impurity in Famotidine (F102250)
Bis[(2-guanidino-4-thiazolyl)methyl]disulfide Preparation Products And Raw materials
N-(Aminosulfonyl)-3-chloropropanamide [3-[[[2-(DiaMinoMethyleneaMino)-4-thiazolyl]Methyl]thio]propionyl]sulfaMide Hydrochloride (FaMotidine IMpurity) Sulfamide FAMOTIDINE RELATED COMPOUND B 3-HYDROXY-PROPIONAMIDINE 2-(4-(CHLOROMETHYL)THIAZOL-2-YL)GUANIDINE 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoyl propanamide (S)-((2-Guanidino-4-thiazolyl)methylisothiourea dihydrochloride 3-(2-Guanidino-thiazol-4-yl-methylthio)-propionitrile 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER Famotidine 3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylsulphinyl]-N-sulphamoylpropanamidine FaMotidine Acid IMpurity 3-Hydroxypropionic acid Famotidine Related Compound A Hydrochloride FaMotidine Acid IMpurity Methyl Ester 3-HYDROXYPROPIONAMIDE Famotidine EP Impurity A

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