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| | Lurasidone hydrochloride Basic information |
| Product Name: | Lurasidone hydrochloride | | Synonyms: | Lurasidonhydrochloride;Lurasidonhydrochlorid;(3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride;(3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride;Lurasidone Hydrochloride Tablets;Exodiene Lurasidone;Lurasidone HCl / Lurasidone Hydrochloride;(3aR,4R,7S,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl) | | CAS: | 367514-88-3 | | MF: | C28H37ClN4O2S | | MW: | 529.14 | | EINECS: | 682-423-6 | | Product Categories: | Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;367514-88-3 | | Mol File: | 367514-88-3.mol |  |
| | Lurasidone hydrochloride Chemical Properties |
| Melting point | 198-205°C | | Fp | 9℃ | | storage temp. | Refrigerator | | solubility | DMSO : 10 mg/mL (18.90 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | | form | Powder | | InChIKey | PQXKDMSYBGKCJA-CVTJIBDQSA-N | | SMILES | O=C1N(C(=O)[C@@]2([H])[C@]3([H])CC[C@@]([H])(C3)[C@@]12[H])C[C@@H]1CCCC[C@H]1CN1CCN(C2=NSC3=CC=CC=C23)CC1.Cl |&1:5,7,11,14,17,22,r| |
| | Lurasidone hydrochloride Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively | | Uses | An antipsychotic used for treatment of schizophrenia. | | Definition | ChEBI: A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia. |
| | Lurasidone hydrochloride Preparation Products And Raw materials |
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