2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE

2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Basic information
Product Name:2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE
Synonyms:2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE;2-[2-(2-methoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione;Carvedilol Impurity 4;Carvedilol Impurity XA;Carvedilol Impurity 17;2-(2-(2-Methoxyphenoxy)ethyl)isoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-[2-(2-methoxyphenoxy)ethyl]-
CAS:26646-63-9
MF:C17H15NO4
MW:297.31
EINECS:
Product Categories:
Mol File:26646-63-9.mol
2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Structure
2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Chemical Properties
Melting point 102-108 °C
Boiling point 449.5±25.0 °C(Predicted)
density 1.278±0.06 g/cm3(Predicted)
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
pka-2.27±0.20(Predicted)
color White to Off-White
Safety Information
MSDS Information
2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Usage And Synthesis
UsesN-[2-(o-Methoxyphenoxy)ethyl]phthalimide is a useful synthetic intermediate in the synthesis of Carvedilol (C184625); a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.
2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Preparation Products And Raw materials
Preparation Products2-(2-Methoxyphenoxy)ethylamine
Carvedilol Bis-carbazole 3-(9H-Carbazol-4-yloxy)-1,2-propanediol 5-(OxiranylMethoxy)-2,3,4,9-tetrahydrocarbazole Carvedilol Impurity DBA 2-(4-METHOXYPHENOXY)ETHYLAMINE 1,3-Bis(9H-carbazol-4-yloxy)-2-propanol (Carvedilol Impurity) Carvedilol Impurity 2 Carvedilol Impurity COH AURORA KA-7735 1,2-bis(2-methoxyphenoxy)ethane AURORA 2926 AURORA 8880 AURORA 8146 AURORA 8187 2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE AURORA 8188 AURORA 8622 AURORA 12314

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