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| | Isowightenon Basic information |
| Product Name: | Isowightenon | | Synonyms: | 3'-(3-Methyl-2-butenyl)-4',5,7-trihydroxyisoflavone;3'-Dimethylallylgenistein;4',5,7-Trihydroxy-3'-(3-methyl-2-butenyl)isoflavone;4',5,7-Trihydroxy-3'-prenylisoflavone;Isowightenon;Isowighteone;Isowigtheone;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]- | | CAS: | 68436-47-5 | | MF: | C20H18O5 | | MW: | 338.35 | | EINECS: | | | Product Categories: | | | Mol File: | 68436-47-5.mol |  |
| | Isowightenon Chemical Properties |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder | | color | Yellow |
| | Isowightenon Usage And Synthesis |
| Uses | Isowighteone is a natural product derivative of Genistein (G350000). Genistein exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol. | | Definition | ChEBI: Isowighteone is a member of the class of 7-hydroxyisoflavones that is isoflavone substituted by hydroxy groups at positions 5, 7 and 4' and a prenyl group at position 3'. It has been isolated from Ficus mucuso. It has a role as a plant metabolite. It is functionally related to an isoflavone. | | target | Antifection |
| | Isowightenon Preparation Products And Raw materials |
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