Ziconotide acetate

Ziconotide acetate Basic information

Product Name:	Ziconotide acetate
Synonyms:	OMEGA-CONOTOXIN MVIIA;OMEGA-CGTX MVII A;ZICONOTIDE ACETATE;snx111;H-CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2;H-CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2 (DISULFIDE BRIDGE: 1-16, 8-20, AND 15-25);CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2;CKGKGAKCSRLMYDCCTGSCRSGKC-NH2 (DISULFIDE BRIDGE: 1-16,8-20, AND 15-25)
CAS:	107452-89-1
MF:	C102H172N36O32S7
MW:	2639.13
EINECS:
Product Categories:	Peptide;107452-89-1
Mol File:	107452-89-1.mol

Ziconotide acetate Chemical Properties

density	1.60±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO (Slightly, Sonicated), Methanol (Slightly)
form	Solid
color	White to Off-White
InChIKey	BPKIMPVREBSLAJ-QTBYCLKRSA-N

Safety Information

MSDS Information

Provider	Language
Ziconotide acetate	English
SigmaAldrich	English

Ziconotide acetate Usage And Synthesis

Uses	Ziconotide, the peptide toxin of the Conus magus (cone snail) is a selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective.
Brand name	Prialt (Elan).
General Description	ω-Conotoxin MVIIA functions as a selective inhibitor of N-type voltage-sensitive calcium channels (VSCCs). It has analgesic and neuroprotective effects. ω-Conotoxin MVIIA is used to treat neuropathic pain.
Biochem/physiol Actions	Neuronal N-type Ca2+ channel blocker in mammalian and amphibian brain; blocks release of GABA and glutamate at neuronal synapses.

Ziconotide acetate Preparation Products And Raw materials

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