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| | 4-Phenylpyridine Basic information |
| | 4-Phenylpyridine Chemical Properties |
| Melting point | 69-73 °C (lit.) | | Boiling point | 274-275 °C (lit.) | | density | 1.1088 (rough estimate) | | refractive index | 1.6210 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform, Methanol | | form | Crystalline Powder | | pka | 5.45±0.10(Predicted) | | color | Light yellow to beige | | Water Solubility | SOLUBLE | | BRN | 110490 | | LogP | 2.590 | | CAS DataBase Reference | 939-23-1(CAS DataBase Reference) | | NIST Chemistry Reference | 4-phenyl-pyridine(939-23-1) | | EPA Substance Registry System | 4-Phenylpyridine (939-23-1) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | UT7141000 | | F | 10 | | HazardClass | IRRITANT, KEEP COLD | | HS Code | 29333990 |
| | 4-Phenylpyridine Usage And Synthesis |
| Chemical Properties | LIGHT YELLOW TO BEIGE CRYSTALLINE POWDER | | Uses | 4-Phenylpyridine is a useful synthetic intermediate. 4-Phenylpyridine has been shown to induce inhibition of mitochondrial respiration in mice. | | Definition | ChEBI: 4-Phenylpyridine is a phenylpyridine. | | Synthesis Reference(s) | Journal of the American Chemical Society, 78, p. 1702, 1956 DOI: 10.1021/ja01589a060
Synthetic Communications, 21, p. 619, 1991 DOI: 10.1080/00397919108020828
Tetrahedron Letters, 36, p. 5247, 1995 DOI: 10.1016/0040-4039(95)00983-J | | Enzyme inhibitor | This substituted pyridine (FW = 155.20 g/mol; CAS 939-23-1; M.P. = 69- 73°C; B.P. = 274-275°C), which occurs naturally and is likewise a manmade pollutant, inhibits human placental aromatase, Ki = 0.36 μM, monoamine oxidase, and NADH dehydrogenase. 4-Phenylpyridine is also an effective inhibitor of mitochondrial complex I. Note that it both occurs naturally and is an environmental pollutant. |
| | 4-Phenylpyridine Preparation Products And Raw materials |
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