STRYCHNINE

STRYCHNINE Basic information
Product Name:STRYCHNINE
Synonyms:STRYCHNINE ALKALOID;STRYCHNINE HEMISULFATE;STRYCHNINE HEMISULFATE SALT;STRYCHNINE SULFATE;STRYCHNINE SULPHATE;antivampire;strychiniumsulfate;Strychnine Sulfate BPC
CAS:60-41-3
MF:C21H22N2O2.1/2H2O4S
MW:766.91
EINECS:200-477-7
Product Categories:Inhibitors;Amino Acids;I - Z;Modified Amino Acids;Alkaloids;Biochemistry;for Resolution of Acids;Indole Alkaloids;Optical Resolution;Synthetic Organic Chemistry
Mol File:60-41-3.mol
STRYCHNINE Structure
STRYCHNINE Chemical Properties
Melting point 284-286 °C(lit.)
density 1.0926 (rough estimate)
refractive index 1.6000 (estimate)
solubility chloroform: clear to hazy
pka8.26(at 25℃)
Merck 8855
CAS DataBase Reference60-41-3(CAS DataBase Reference)
EPA Substance Registry SystemStrychnine sulfate (60-41-3)
Safety Information
Hazard Codes T+,N
Risk Statements 27/28-50/53-26/28
Safety Statements 36/37-45-60-61-28-13
RIDADR UN 1692 6.1/PG 1
WGK Germany 3
RTECS WL2550000
HazardClass 6.1(a)
PackingGroup I
ToxicityLD50 orally in rats: 5 mg/kg, E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972)
MSDS Information
ProviderLanguage
SigmaAldrich English
STRYCHNINE Usage And Synthesis
Chemical PropertiesStrychnine is a colorless crystalline prisms or white powder. It is odorless; with a bitter taste
Usescentral stimulant
UsesChiefly in poison baits for rodents.
General DescriptionColorless, odorless, very bitter crystals or white crystalline powder. Has been used as a tonic and stimulant in veterinary medicine. Registered as a rodenticide in the U.S.
Reactivity ProfileSTRYCHNINE is an alkaloid derivative. STRYCHNINE is a base and forms water soluble salts with acids. Avoid alkalis, alkali carbonates and bicarbonates, benzoates, dichromates, bromides, iodides, tannic and picric acids, salicylates, borax, gold chloride and other alkaloid precipitants, piperazine, potassium-mercuric iodide. Protect from light. [EPA, 1998] STRYCHNINE is incompatible with the following: Strong oxidizers .
Health HazardViolent poison!. Lowest published lethal dose orally in humans is 30 mg/kg.
Fire HazardWhen heated to decomposition, STRYCHNINE emits very toxic fumes of sulfur oxides and nitrogen oxides. Avoid alkalies, alkali carbonates and bicarbonates, benzoates, dichromates, bromides, iodides, tannic and picric acids, salicylates, borax, gold chloride and other alkaloid precipitants, piperazine, potassium-mercuric iodide. Protect from light.
Safety ProfilePoison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also STRYCHNINE and SULFATES
Potential Exposurede, requiring a certified applicator. Strychnine is an alkaloid compound that has been widely used as a rodenticide/bait to kill rodents; a medicine, respiratory stimulant. A potential danger to those involved in the extraction the seeds of the Strychnos nux vomica, Strychnos ignatii (S. sancta Ingnatius), and Strychnos tiente (Upas tree); formulation or application of this rodent poison. The sulfate is used to kill gophers and moles. A common adulterant in illicit street drugs. Listed as a potential WMD biotoxin.
ShippingUN1692 Strychnine or strychnine salts, Hazard Class: 6.1; Labels: 6.1-Poisonous material.
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Dangerous when heated; forms toxic fumes, including nitrogen oxides. In the body, caffeine may increase the strychnine effect.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposal. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Careful incineration has been recommended for disposal. Two procedures are suggested. Pour or sift onto a thick layer of sand and soda ash mixture (90-10). Mix and shovel into a heavy paper box with much paper packing Burn in incinerator. Fire may be augmented by adding excelsior and scrap wood. Stay on the upwind side. Waste may be dissolved in flammable solvent (alcohols, benzene, etc.) and sprayed into fire box of an incinerator with afterburner and scrubber.
STRYCHNINE Preparation Products And Raw materials
strychnine-insensitive glycine receptor STRYCHNINE HYDROCHLORIDE, DIHYDRATE STRYCHNINE SULFATE, 5-HYDRATE STRYCHNINE PHOSPHATE STRYCHNINE, [BENZENE-3H]-,STRYCHNINE, [BENZENE RING-3H]- STRYCHNINE (BASE AND/OR UNSPECIFIED SALTS) STRYCHNINE SOLUTION 100UG/ML IN METHANOL 5ML STRYCHNINE SULFATE PENTAHYDRATE STRYCHNINE BASE FERRIC STRYCHNINE CITRATE,IRON (III) STRYCHNINE CITRATE STRYCHNINE SOLUTION 100UG/ML IN METHANOL 1ML STRYCHNINE [3H(G)] Strychnine&It'SSalts Brucine sulfate. STRYCHNINE SOLUTION 100UG/ML IN METHANOL 5X1ML Dimethoxy strychnine sulfate METHYL STRYCHNINE strychnine receptor

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