3-Cyano-2,6-dihydroxy-4-methylpyridine

3-Cyano-2,6-dihydroxy-4-methylpyridine Basic information
Product Name:3-Cyano-2,6-dihydroxy-4-methylpyridine
Synonyms:3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-4-methyl-2-oxo-;sodium 6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile;2,6-Dihydroxy-4-methyl-3-pyridinecarbonitrile 99%;1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarbonitril;2,6-DIHYDROXY-4-METHYL-3-PYRIDINECARBONITRILE;2,6-DIHYDROXY-3-CYANO-4-METHYLPYRIDINE;2,6-DIHYDROXY-4-METHYLNICOTINONITRILE;2,6-DIHYDROXY-4-METHYLPYRIDINE-3-CARBONITRILE
CAS:5444-02-0
MF:C7H6N2O2
MW:150.13
EINECS:226-639-7
Product Categories:Intermediates of Dyes and Pigments;alcohol|cyanide;Heterocyclic Compounds;Pyridines;Alcohols;Monomers;Polymer Science;bc0001
Mol File:5444-02-0.mol
3-Cyano-2,6-dihydroxy-4-methylpyridine Structure
3-Cyano-2,6-dihydroxy-4-methylpyridine Chemical Properties
Melting point 315 °C (dec.)(lit.)
Boiling point 339.0±42.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
pka3.59±0.58(Predicted)
form powder to crystal
color White to Almost white
CAS DataBase Reference5444-02-0(CAS DataBase Reference)
EPA Substance Registry System3-Pyridinecarbonitrile, 1,2-dihydro-6-hydroxy-4-methyl-2-oxo- (5444-02-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 2933399990
MSDS Information
ProviderLanguage
SigmaAldrich English
3-Cyano-2,6-dihydroxy-4-methylpyridine Usage And Synthesis
Chemical PropertiesPale yellow solid
Uses3-Cyano-2,6-dihydroxy-4-methylpyridine is a synthetic human uridine phosphorylase-1 inhibitor, reduces HepG2 cell proliferation through cell cycle arrest and senescenceis and is used in the synthesis of disperse dyes. Also used in the synthesis of mGluR5 non-competitive antagonists.
3-Cyano-2,6-dihydroxy-4-methylpyridine Preparation Products And Raw materials
Preparation ProductsC.I. Disperse Yellow 103-->3-cyano-2,6-dibromo-4-methylpyridine-->2,6-diamino-3-cycno-4-methylpyridine-->4-(bromomethyl)nicotinonitrile
Methylparaben Methyl 3-Cyano-4-methylpyridine Methyl propyl carbonate 2-Chloro-3-cyanopyridine Bensulfuron methyl 3-Cyano-2,6-dihydroxy-4-methylpyridine Parathion-methyl Azamethiphos 2,6-Lutidine 2,4,6-Collidine Thiophanate-methyl Methyl acrylate 2-CYANO-4-METHYLPYRIDINE Cyano Methyl acetate Methyl bromide METHYL THIOPHENE-2-CARBOXYLATE

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