lamivudine sulfoxide

lamivudine sulfoxide Basic information
Product Name:lamivudine sulfoxide
Synonyms:4-amino-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one;Lamivudine EP Impurity H;lamivudine sulfoxide;Lamivudine Impurity 7(Lamivudine EP Impurity G);Lamivudine Impurit Ⅳ:4-amino-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one;Lamivudine EP IMP G;2(1H)-Pyrimidinone, 4-amino-1-[(2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI);Lamivudine (S)-Sulfoxide
CAS:160552-55-6
MF:C8H11N3O4S
MW:245.25
EINECS:
Product Categories:
Mol File:160552-55-6.mol
lamivudine sulfoxide Structure
lamivudine sulfoxide Chemical Properties
Melting point >220°C (dec.)
Boiling point 601.7±65.0 °C(Predicted)
density 1.93±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka13.46±0.10(Predicted)
form Solid
color White
Safety Information
MSDS Information
lamivudine sulfoxide Usage And Synthesis
UsesLamivudine (S)-Sulfoxide (Lamivudine EP Impurity G) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
lamivudine sulfoxide Preparation Products And Raw materials
lignocaine N-oxide (2R-cis)-5-(4-aMino-2-oxo-1(2H)-pyriMidinyl)-1,3-oxathiolane-2-carboxylic Acid Ticagrelor Sulfone 3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid Olaparib impurity 1 Lamivudine EP Impurity A Tirofiban hydrochloride Impurity 6 Aids004768 Lamivudine Salicylic acid Lamivudine Impurity 1 Cytosine 5'-Epi-LaMivudine TROXACITABINE 4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one Lamivudine EP Impurity B ent-LaMivudine Uracil

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