ChemicalBook Product Catalog Organic Chemistry Organic fluorine compound Fluorobenzaldehyde series 2,6-Difluorobenzaldehyde

2,6-Difluorobenzaldehyde

2,6-Difluorobenzaldehyde Basic information
Product Name:2,6-Difluorobenzaldehyde
Synonyms:TIMTEC-BB SBB006685;2,6-Difluorobenzaldehyde,97%;2,6-DIFLUOROBENZALDEHYDE;3,4,5-triflurobenzenenitrile;2,6-Difluorobenzaldehyde 98%;2,6-Difluorobenzaldehyde98%;2,6-DIFLUORLOBENZALDEHYDE;2-6-Difluorbenzaldehyd
CAS:437-81-0
MF:C7H4F2O
MW:142.1
EINECS:610-142-0
Product Categories:Fluorine series;Building Blocks;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Fluorobenzene;Carbonyl Compounds;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;API intermediates;Miscellaneous;Aldehydes;Other Fluorinated Organic Building Blocks;C7;Carbonyl Compounds;Aryl Fluorinated Building Blocks
Mol File:437-81-0.mol
2,6-Difluorobenzaldehyde Structure
2,6-Difluorobenzaldehyde Chemical Properties
Melting point 15-17 °C (lit.)
Boiling point 82-84 °C/15 mmHg (lit.)
density 1.317 g/mL at 25 °C (lit.)
vapor pressure 40.1-900hPa at 94.5-189℃
refractive index n20/D 1.502(lit.)
Fp 164 °F
storage temp. 2-8°C
form Liquid
color Clear light yellow to bright yellow
Specific Gravity1.317
Sensitive Air Sensitive
BRN 1935273
InChIKeySOWRUJSGHKNOKN-UHFFFAOYSA-N
LogP1.46 at 25℃ and pH2
Surface tension73.1mN/m at 1g/L and 20℃
CAS DataBase Reference437-81-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39-37/39-36/37
WGK Germany 2
F 10-23
HazardClass IRRITANT
HS Code 29130000
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
2,6-Difluorobenzaldehyde Usage And Synthesis
Chemical Propertiesclear light yellow to bright yellow liquid
Uses2,6-Difluorobenzaldehyde can be used as a reactant to synthesize:
  • 5-Cyano-6-(2,6-difluorophenyl)-5,6-dihydro-2-thiouracil via one-pot cyclocondensation reaction with ethyl cyanoacetate and thiourea.
  • 1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-benzimidazole by reacting with 1,2-phenylenediamine in the presence of a catalytic amount of p-toluenesulfonic acid.
  • (3E)-4-(2,6-Difluorophenyl)-3-buten-2-one by Wittig olefination reaction with acetylmethylidenetriphenyl phosphorane.
  • Methyl 4-fluorobenzo[b]thiophene-2-carboxylate by treating with methyl thioglycolate in the presence of K2CO3.

2,6-Difluorobenzaldehyde Preparation Products And Raw materials
Raw materials2-Chloro-6-fluorobenzaldehyde
Preparation Products2,6-Difluorobenzyl bromide-->2,6-Difluorobenzoic acid-->Benzo[b]thiophene, 4-fluoro- (9CI)-->4-FLUORO (1H)INDAZOLE-->2,6-Difluorophenol
2,3,5,6-Tetrafluorobenzoic acid 2,6-Difluorobenzaldehyde Transfluthrin 2,4-DIFLUOROBENZALDEHYDE,2,4-Difluorobenzaldehyde 98%,2,4-Difluorobenzaldehyde98% 2,3,6-TRIFLUOROBENZOIC ACID fluorobenzaldehyde 2,3,4,5,6-PENTAFLUOROBENZAMIDE Tetrafluoroterephthalic acid 2,6-DIFLUOROBENZOPHENONE 4-Fluorobenzaldehyde 1-(2,6-Difluorophenyl)ethan-1-one 1,2-Difluorobenzene 2,3-DIFLUOROBENZALDEHYDE,2,3-Difluorobenzaldehyde,98%,2,3-Difluorobenzaldehyde 98% 4-AMINO-2,3,5,6-TETRAFLUOROBENZOIC ACID Florfenicol 3,4-Difluorobenzaldehyde 98%,3,4-Difluorobenzaldehyde,98%,3,4-DIFLUOROBENZALDEHYDE 2,6-Difluorobenzoyl chloride 1,3-Difluorobenzene
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