Ligustrazine Hydrochloride

Ligustrazine Hydrochloride Basic information
Product Name:Ligustrazine Hydrochloride
Synonyms:Chuanxiongzine Hydrochlorid;Chuanxiongzine Hydrochloride, TetraMethylpyrazine hydrochloride;LIGUSTRAZOINEHYDROCHLORIDE;2,3,5,6-Tetramethylpyrazine hydrochloride;Tetramethylpyrazine HCl;Tetrapyrazine HCl;Tetramethylpyrazine Hydrochloride USP/EP/BP;Tetramethylphrazine USP/EP/BP
CAS:76494-51-4
MF:C8H12N2.ClH
MW:172.658
EINECS:1592732-453-0
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File:76494-51-4.mol
Ligustrazine Hydrochloride Structure
Ligustrazine Hydrochloride Chemical Properties
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form powder
color White
Safety Information
MSDS Information
Ligustrazine Hydrochloride Usage And Synthesis
DescriptionLigustrazine Hydrochloride, its main function is to inhibit platelet aggregation and prevent thrombosis. At the same time, it can resist vascular damage caused by serotonin and bradykinin, increase capillary resistance, reduce capillary permeability, and prevent edema caused by increased vascular permeability. Clinically, it is mainly used for occlusive syndrome, thrombophlebitis, capillary bleeding, etc. The market demand for this product is large.
Chemical PropertiesWhite crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dried root of Ligusticum chuanxiong hort.
UsesLigustrazine Hydrochloride has the effect of antiplatelet coagulation, dilation of small arteries, treatment of occlusive cerebrovascular disease.
ApplicationLigustrazine Hydrochloride can be used to treat cerebral insufficiency, cerebral thrombosis, cerebral embolism and other ischemic vascular diseases, such as coronary atherosclerotic heart disease, vasculitis, etc. When the patient is in the acute stage of the disease, intravenous drip is generally used.
targetIL Receptor | NOS | NO | TGF-β/Smad | TXA2 - PGI2 | VEGFR
Ligustrazine Hydrochloride Preparation Products And Raw materials
CUCURBITACIN IIA Coptisine chloride JATRORRHIZINE HCL(RG) SANGUINARINE Berberine hydrochloride 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride STACHYDRINE HYDROCHLORIDE Betaine hydrochloride SECO-ISOLARICIRESINOL DIGLUCOSIDE SINOMENINE HYDROCHLORIDE Lycorine hydrochloride Corydaline Arbutin TETRAHYDROPALMATINE HYDROCHLORIDE Ursolic acid 5-(4-CHLOROPHENYL)-6-(5-CHLOROPYRIDIN-2-YL)PYRAZINE-2,3-DICARBONITRILE Ligustrazine Hydrochloride Tetramethylpyrazine

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