Curdione

Curdione Basic information

Product Name:	Curdione
Synonyms:	(3S,6E,10S)-6,10-Dimethyl-3-propan-2-ylcyclodec-6-ene-1,4-dione;Curdione;Germacr-1(10)-ene-5,8-dione;6,10-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione;AaruginousTurmericRhizome;Curcuma two ketone;Curdione, >99%;Curcuma Tuber Extract
CAS:	13657-68-6
MF:	C15H24O2
MW:	236.35
EINECS:
Product Categories:	chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:	13657-68-6.mol

Curdione Chemical Properties

Melting point	61.5-62.0 °C
Boiling point	318.82°C (rough estimate)
density	0.93
refractive index	1.4700 (estimate)
Fp	130℃
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form	Cryst.
LogP	3.120 (est)
NIST Chemistry Reference	6,10-Dimethyl-3-(1-methylethyl)-6-cyclodecene-1,4-dione(13657-68-6)

Safety Information

HS Code

29143990

MSDS Information

Curdione Usage And Synthesis

Chemical Properties	Colorless prismatic crystal (anhydrous ethanol), melting point 61～62℃, [α]25D+26°(c=1, chloroform), easily soluble in ether and chloroform, slightly soluble in petroleum ether.
Uses	Curdione can be used for content determination, identification and pharmacological experiments, etc. Pharmacological and pharmacological effects: It has obvious inhibitory effect on mouse sarcoma 37, mouse cervical cancer U14 and mouse Ehrlich ascites cancer, and can make cancer cells cross necrosis. Ehrlich ascites carcinoma treated with this product can successfully obtain active immunity in mice. It has good curative effect in clinical treatment of cervical cancer.
Definition	ChEBI: Curdione is a germacrane sesquiterpenoid.
Biological Activity	Curdione is a sesquiterpenoid substance isolated from Curcuma zedoary, with high biological activity, which has the effect of inhibiting platelet aggregation and resisting thrombosis.

Curdione Preparation Products And Raw materials

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