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Hydroxy Bosentan

Hydroxy Bosentan Basic information
Product Name:Hydroxy Bosentan
Synonyms:4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide;Ro 48-863;Ro 48-8634;Bosentan HydroxyMethyl IMpurity;Bosentan Hydroxy;Bosentan-Hydroxy methyl-Imp;N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide;Benzenesulfonamide, 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-
CAS:253688-60-7
MF:C27H29N5O7S
MW:567.61
EINECS:
Product Categories:Aromatics;Heterocycles;Bases & Related Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Nucleotides;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:253688-60-7.mol
Hydroxy Bosentan Structure
Hydroxy Bosentan Chemical Properties
Melting point 128-132°C
Boiling point 783.9±70.0 °C(Predicted)
density 1.372±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMSO: soluble
form A crystalline solid
pka3.90±0.10(Predicted)
Safety Information
HS Code 29339900
MSDS Information
Hydroxy Bosentan Usage And Synthesis
Chemical PropertiesHydroxy Bosentan is White Powder
UsesHydroxy Bosentan is a metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator
UsesThe active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.
Hydroxy Bosentan Preparation Products And Raw materials
2,2-Bis(hydroxymethyl)propionic acid Hydroxy Bosentan-d4 DESMETHYL BOSENTAN BenzenesulfonaMide, N,N'-[1,2-ethanediylbis[oxy[5-(2-Methoxyphenoxy)[2,2'-bipyriMidine]-6,4-diyl]]]bis[4-(1,1-diMethylethyl)- Posaconazole iMpurity Hydroxy Bosentan-d6 BenzenesulfonaMide, N-[1,6-dihydro-5-(2-Methoxyphenoxy)-6-oxo[2,2'-bipyriMidin]-4-yl]-4-(1,1-diMethylethyl)- CARBOXYMETHYLCELLULOSE SODIUM SALT Tetrakis(hydroxymethyl)phosphonium sulfate HYDROXY DESMETHYL BOSENTAN 4-(2-Hydroxy-1,1-dimethylethyl)benzenesulfonamide 5,6-Dimethoxypyrimidin-4-ylamine Hydroxy Bosentan Bosentan 4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE DIHYDRATE Bosentan hydrate 2,2'-BIPYRIMIDINE 4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE
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