procyclidine

procyclidine Basic information
Product Name:procyclidine
Synonyms:Kemadrine;Vagosin;α-Cyclohexyl-α-phenyl-1-pyrrolidine-1-propanol;1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;procyclidine;Tricyclamol;1-Pyrrolidinepropanol, α-cyclohexyl-α-phenyl-;procyclidine USP/EP/BP
CAS:77-37-2
MF:C19H29NO
MW:287.44
EINECS:201-023-0
Product Categories:
Mol File:77-37-2.mol
procyclidine Structure
procyclidine Chemical Properties
Melting point 85.5-86.5°
Boiling point 429.73°C (rough estimate)
density 0.9954 (rough estimate)
refractive index 1.5180 (estimate)
pka14.21±0.29(Predicted)
Water Solubility 1.055mg/L(22.5 ºC)
Safety Information
Hazardous Substances Data77-37-2(Hazardous Substances Data)
MSDS Information
procyclidine Usage And Synthesis
UsesAntiparkinsonian; relaxant (skeletal muscle).
DefinitionChEBI: A tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.
Brand nameKemadrin (Monarch).
SynthesisProcyclidine, 1-cyclohexyl-1-phenyl-3-pirrolidinopropan-1-ol (10.2.3), is synthesized in the exact same manner, except beginning with 2-(1-pyrrolidino) propiophenone [28–32].
procyclidine Preparation Products And Raw materials
1-PHENYL-1-HEXANOL (1S,2S)-(+)-Pseudoephedrine hydrochloride 3-PHENYL-3-PENTANOL 2-METHYL-1-PHENYL-1-PENTANOL procyclidine N-OCTYL PYRROLIDINE 2-METHYL-4-(METHYLAMINO)BUTAN-2-OL 3-AMINO-1-PHENYL-PROPAN-1-OL 2-PHENYL-2-PENTANOL Gamfexine 1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL PROCYCLIDINE HYDROCHLORIDE Cyclohexyl(phenyl)methanol 2-METHYL-1-PHENYL-1-BUTANOL 1-PHENYL-1-HEPTANOL 3-DIMETHYLAMINO-1-PHENYL-PROPAN-1-OL 1-(3-HYDROXYPROPYL)-PYRROLIDINE tricyclamol chloride

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