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| | Sulfobromophthalein sodium Basic information |
| Product Name: | Sulfobromophthalein sodium | | Synonyms: | BROMOSULFOPHTHALEIN;BROMOSULFOPHTHALEIN SODIUM SALT;BROMO SULPHALEIN;BROMOSULPHALEIN DISODIUM SALT;3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3h)-isobenzofuranylidene)bis(6-hydroxy-benzenesulfonic acid) disodium salt;bromsulfalein sodium;SULFORBROMOPHTHALEINSODIUMHYDRATE;PHENOLTETRABROMOPHTHALEIN-3',3''-DISULFONIC ACID DISODIUM SALT | | CAS: | 123359-42-2 | | MF: | C20H13Br4NaO11S2 | | MW: | 836.04 | | EINECS: | 626-376-1 | | Product Categories: | | | Mol File: | 123359-42-2.mol |  |
| | Sulfobromophthalein sodium Chemical Properties |
| Melting point | >235°C (dec.) | | storage temp. | room temp | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | Crystalline Powder | | color | White | | CAS DataBase Reference | 123359-42-2(CAS DataBase Reference) |
| | Sulfobromophthalein sodium Usage And Synthesis |
| Description | A blue dye used in the assessment of
hepatobiliary dysfunction. The concentration in plasma is
monitored since dye removal from the blood is delayed in
hepatic dysfunction. Experimentally the appearance of sulfobromphthalein in the bile can also be measured. | | Chemical Properties | White, crystalline powder; odorless; bit-
ter taste. Hygroscopic; soluble in water; insoluble
in alcohol and acetone.
| | Uses | Medicine (diagnostic aid).
| | Uses | Sulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto-β-boswellic acid (KBA) and 3-acetyl-11-keto-β-boswellic acid (AKBA) with organic anion transporter OATP1B3. | | Biochem/physiol Actions | Sulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20. |
| | Sulfobromophthalein sodium Preparation Products And Raw materials |
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