1-Bromo-2,3-epoxypropane

1-Bromo-2,3-epoxypropane Basic information
Product Name:1-Bromo-2,3-epoxypropane
Synonyms:1-BROMO-2,3-EPOXYPROPANE;epibromhydrine(french);epibromohydrin(ebh);Glycidyl bromide;halogenatedalkylepoxides;Oxirane, (bromomethyl)-;BROMOMETHYLOXIRANE;3-bromo-1,2-epoxy-propan
CAS:3132-64-7
MF:C3H5BrO
MW:136.98
EINECS:221-525-3
Product Categories:Oxiranes;Simple 3-Membered Ring Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:3132-64-7.mol
1-Bromo-2,3-epoxypropane Structure
1-Bromo-2,3-epoxypropane Chemical Properties
Melting point −40 °C(lit.)
Boiling point 134-136 °C(lit.)
density 1.67
refractive index n20/D 1.482(lit.)
Fp 133 °F
storage temp. 2-8°C
solubility Chloroform (Soluble), Methanol (Sparingly)
form Oil
color Colourless
Specific Gravity1.668 (20/4℃)
BRN 79786
Stability:Stable. Incompatible with acids, bases, oxidizing agents, many of the more active metals.
InChIKeyGKIPXFAANLTWBM-UHFFFAOYSA-N
CAS DataBase Reference3132-64-7(CAS DataBase Reference)
NIST Chemistry Reference1-Bromo-2,3-epoxypropane(3132-64-7)
EPA Substance Registry SystemEpibromohydrin (3132-64-7)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38-40
Safety Statements 26-36/37
RIDADR UN 2558 6.1/PG 1
WGK Germany 2
RTECS TX4115000
HazardClass 6.1(a)
PackingGroup I
HS Code 29109000
Hazardous Substances Data3132-64-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
1-Bromo-2,3-epoxypropane English
SigmaAldrich English
1-Bromo-2,3-epoxypropane Usage And Synthesis
Chemical Propertiescolourless liquid
UsesBromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies.
DefinitionChEBI: An epoxide that is oxirane substituted by a bromomethyl group at position 2.
General DescriptionA colorless volatile liquid. Flash point 22°F. Slightly soluble in water and denser than water. Toxic by inhalation and ingestion. A strong skin irritant. Used to make rubber.
Air & Water ReactionsHighly flammable. Slightly soluble in water. Sensitive to prolonged exposure to light and moisture.
Reactivity Profile1-Bromo-2,3-epoxypropane reacts with acids, bases, oxidizing agents, Na, Zn, Al, Mg and their alloys. .
Health HazardTOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire HazardHIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Safety ProfileHuman mutation data reported. A dangerous fire hazard when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Br-. See also BROMIDES.
1-Bromo-2,3-epoxypropane Preparation Products And Raw materials
Preparation ProductsLAURYL GLYCIDYL ETHER-->4-Epoxypropanoxycarbazole-->2,3-EPOXYPROPYL-4-METHOXYPHENYL ETHER-->3-BROMO-1,2-PROPANEDIOL-->2-(FLUOROSULFONYL)DIFLUOROACETYL FLUORIDE-->(S)-2-Oxiranylanisole-->BENZYL GLYCIDYL ETHER-->p-(2,3-Epoxypropoxy)benzyl Alcohol-->2-[(2-ethoxyphenoxy)methyl]oxirane-->tert-butyl N-methyl-N-(oxiran-2-ylmethyl)carbamate
Epichlorohydrin 1-Bromo-2-methoxyethane 2-Bromopropane 3-Bromo-1-propanol Propane 1-BROMO-2-PROPANOL (R)-Styrene oxide Hexafluoropropylene oxide ETHYLENE OXIDE 1-Bromo-2,3-epoxypropane 3-Bromoanisole Styrene oxide Bromine 1,2-Dibromopropane 1,2,3-Tribromopropane Isobutylene oxide Propylene oxide (2S,3S)-4-BROMO-CIS-2,3-EPOXYBUTYL (1S)- 10-CAMPHORSULFONATE

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