4,4'-OXYBIS(PHENYL ISOCYANATE)

4,4'-OXYBIS(PHENYL ISOCYANATE) Basic information
Product Name:4,4'-OXYBIS(PHENYL ISOCYANATE)
Synonyms:OXYBIS(4-PHENYL ISOCYANATE);1,1’-oxybis[4-isocyanato-benzen;4,4'-OXYBIS(PHENYL ISOCYANATE);4,4'-Diisocyanato[1,1'-oxybisbenzene];4,4'-Oxybis(isocyanatobenzene);Oxybis(1,4-phenylene)bisisocyanate;Oxybis(1,4-phenylene)diisocyanate;Oxybis(4-phenyl isocyanate),99%
CAS:4128-73-8
MF:C14H8N2O3
MW:252.22
EINECS:
Product Categories:Isocyanates;Nitrogen Compounds;Organic Building Blocks
Mol File:4128-73-8.mol
4,4'-OXYBIS(PHENYL ISOCYANATE) Structure
4,4'-OXYBIS(PHENYL ISOCYANATE) Chemical Properties
Melting point 64-68 °C(lit.)
Boiling point 196 °C5 mm Hg(lit.)
density 1.2700 (rough estimate)
refractive index 1.5910 (estimate)
solubility Acetonitrile (Soluble)
form Solid
color White to Off-White
Stability:Moisture Sensitive
CAS DataBase Reference4128-73-8
EPA Substance Registry System4,4'-Diisocyanatodiphenyl ether (4128-73-8)
Safety Information
Hazard Codes Xn,T+
Risk Statements 20/21/22-36/37/38-42/43-26-25-21
Safety Statements 23-26-36/37/39-45-36/37-28-22
RIDADR UN 2206 6.1/PG 3
WGK Germany 3
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
4,4'-OXYBIS(PHENYL ISOCYANATE) Usage And Synthesis
Chemical PropertiesWHITE CRYSTALLINE SOLID
Uses4,4'-Bis(isocyanatophenyl)oxide is a reagent used in the synthesis of lipid-conjugated Smac analogs with antitumor activity against human breast cancer cell lines.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.
Reactivity ProfileIsocyanates and thioisocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Polyurethanes are formed by the condensation reaction of diisocyanates with, for example, ethyl glycol.
4,4'-OXYBIS(PHENYL ISOCYANATE) Preparation Products And Raw materials
4,4'-Oxydianiline 4,4'-OXYBIS(PHENYL ISOCYANATE) 4-Methoxyphenyl isocyanate 1,4-Phenylene diisocyanate 4-PHENOXYPHENYL ISOCYANATE

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