ChemicalBook Product Catalog Organic Chemistry Amides Acyclic polyamines and their derivatives Triethylenetetramine Dihydrochloride

Triethylenetetramine Dihydrochloride

Triethylenetetramine Dihydrochloride Basic information
Product Name:Triethylenetetramine Dihydrochloride
Synonyms:N,N'-BIS(2-AMINOETHYL)-1,2-ETHANEDIAMINE DIHYDROCHLORIDE;TRIETHYLENETETRAMINE DIHYDROCHLORIDE;TRIENE;2,2’-ethylenediiminobis(ethylamine)dihydrochloride;2-ethanediamine,n,n’-bis(2-aminoethyl)-dihydrochloride;mk-0681;TriethylenetetraMine Dihydrochloride (Trientine Hydrochloride );1,2-EthanediaMine,N1,N2-bis(2-aMinoethyl)-, hydrochloride (1:2)
CAS:38260-01-4
MF:C6H20Cl2N4
MW:219.16
EINECS:253-854-3
Product Categories:TICAR;Organic Building Blocks;Enzymes;Inhibitors;Nitrogen Compounds;R to Z;Superoxide dismutase;Amine Salts;and Substrates;Biochemicals and Reagents;Building Blocks;Chemical Synthesis;Enzyme Inhibitors;Enzyme Inhibitors by Enzyme
Mol File:38260-01-4.mol
Triethylenetetramine Dihydrochloride Structure
Triethylenetetramine Dihydrochloride Chemical Properties
Melting point 120-125 °C (dec.)
storage temp. 2-8°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
BRN 5961763
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 2
RTECS KH8587085
F 3
HS Code 2921290055
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
Triethylenetetramine Dihydrochloride Usage And Synthesis
DescriptionTrientine hydrochloride is a copper chelating agent recommended for the treatment of Wilson's Disease, especially in patients intolerant of penicillamine therapy. Unlike the latter agent, trientine is not indicated in cystinuria or rheumatoid arthritis.
Chemical Propertieswhite crystalline powder
OriginatorCambridge University (United Kingdom)
UsesTriethylenetetramine Hydrochloride is a selective CuII-chelator; crosslinking agent. Triethylenetetramine is undergoing trials for the treatment of heart failure in patients with diabetes.
Usesantibacterial
UsesAs thermosetting resin; epoxy curing agent; lubricating oil additive; analytical reagent for Cu, Ni.
DefinitionChEBI: Trientine hydrochloride is a secondary amino compound.
Brand nameSyprine (Merck);CUPRID.
General DescriptionPharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Trientine Hydrochloride is administered for relief of symptoms of Wilson′s disease for penicillamine intolerance, hence is employed as an oral medication for the treatment of an inherited defect in copper metabolism.
Triethylenetetramine Dihydrochloride Preparation Products And Raw materials
Raw materialsSulfuric acid-->Sodium chloride-->Triethylenetetramine
(P-CHLORO-PHE5,8)-BRADYKININ H-LEU-ARG-PRO-GLY-NH2 2HCL spantide II ARG-PRO-LYS-PRO-GLN-GLN-P-CHLORO-PHE-P-CHLORO-PHE-GLY-LEU-MET-NH2 FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE AC-3-(2,6-DICHLORO-BZL)-TYR-ILE-ASN-LEU-ILE-D-THR-ARG-GLN-ARG-TYR-NH2 Triethylenetetramine Dihydrochloride SAR-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE TETRAETHYLENEPENTAMINE PENTAHYDROCHLORIDE ambenonium chloride CBZ-L-ALA-ARG-ARG-4-METHOXY-BETA-NAPHTHYLAMIDE 2HCL AC-(PCL)DPHE-(PCL)DPHE-DTRP-SER-TYR-DARG-LEU-ARG-PRO-DALA-NH2 H-D-PHE-PRO-ARG-4M-BETANA 2HCL 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE N-CBZ-VAL-LYS-LYS-ARG 4-METHOXY-BETA-NAPHTHYLAMIDE TRIHYDROCHLORIDE D-VAL-LEU-LYS P-NITROANILIDE DIHYDROCHLORIDE H-VAL-LEU-LYS-PNA 2 HCL VANCOMYCIN HYDROCHLORIDE HYDRATE
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