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| alpha-Angelica lactone Basic information |
Product Name: | alpha-Angelica lactone | Synonyms: | 3-PENTEN-4-OLIDE;4-HYDROXY-3-PENTANOIC ACID GAMMA-LACTONE;4-HYDROXY-3-PENTENOIC ACID GAMMA-LACTONE;4-HYDROXY-3-PENTENOIC ACID G-LACTONE;4-HYDROXY-3-PENTENOIC ACID LACTONE;2,3-Dihydro-5-methyl-2-furanone;3-Pentenoic acid, 4-hydroxy-, gamma-lactone;4-hydroxy-3-pentenoicacigamma-lactone | CAS: | 591-12-8 | MF: | C5H6O2 | MW: | 98.1 | EINECS: | 209-701-8 | Product Categories: | Miscellaneous Natural Products | Mol File: | 591-12-8.mol | |
| alpha-Angelica lactone Chemical Properties |
Safety Statements | 24/25 | RIDADR | NA 1993 / PGIII | WGK Germany | 2 | RTECS | LU5075000 | F | 10-21 | TSCA | Yes | HS Code | 29322090 | Toxicity | LD50 orl-mus: 2800 mg/kg DCTODJ 3,249,80 |
| alpha-Angelica lactone Usage And Synthesis |
Chemical Properties | clear colorless to straw yellow liquid | Chemical Properties | α-Angelica lactone has a sweet, herbaceous odor reminiscent of tobacco. | Occurrence | Reported found in grape, white bread, soy bean and licorice.
| Uses | alpha-Angelicalactone acts as acancer chemopreventive agent. It is used in the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver. It is used in oral care formulations to round out mint notes and in coffee flavors. | Preparation | By dry distillation of levulinic acid | Definition | ChEBI: Alpha-angelica lactone is an angelica lactone and a butenolide. It is functionally related to a but-3-en-4-olide. It is a tautomer of a beta-angelica lactone. | Taste threshold values | Taste characteristics at 100 ppm: sweet, creamy, coconut, vanilla hay and coumarin-like nuances | General Description | α-Angelica lactone, a cyclic lactone that occurs naturally in tobacco, is generally used in tobacco flavoring. | Biochem/physiol Actions | Plant-derived cancer chemopreventive agent. Increases the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver. | Safety Profile | Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits acrid smoke and irritating fumes. |
| alpha-Angelica lactone Preparation Products And Raw materials |
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