Perfluoropropionic anhydride

Perfluoropropionic anhydride Basic information
Product Name:Perfluoropropionic anhydride
Synonyms:Pentafluoropropionic anhydride, PFAA;PENTAFLUORPROPIONSUREANHYDRID;Pentafluoropropionic anhydride,PFPA, Perfluoropropionic anhydride;Perfluoropropanoic anhydride 99%;2,2,3,3,3-Pentafluoropropanoyl 2,2,3,3,3-pentafluoropropanoate;Pentafluoropropionic anhydride, min. 97%;PENTAFLUORPROPIONSREANHYDRID;Bis(2,2,3,3,3-pentafluoropropionic acid)anhydride
CAS:356-42-3
MF:C6F10O3
MW:310.05
EINECS:206-604-2
Product Categories:organofluorine compounds;Analytical and Industrial Enzymes;PFPA - Pentafluoropropionic anhydride;and Substrates;Biochemicals and Reagents;Building Blocks;Acylation Reagent;Carbonyl Compounds;Carboxylic Acid Anhydrides;Chemical Synthesis;Enzymes;-Glucuronidase;-Glucuronidase Drug Analysis Bundle;Inhibitors;Organic Building Blocks;Small molecule;Acylation (GC Derivatizing Reagents);Analytical Chemistry;GC Derivatizing Reagents
Mol File:356-42-3.mol
Perfluoropropionic anhydride Structure
Perfluoropropionic anhydride Chemical Properties
Melting point -43
Boiling point 69-70 °C/735 mmHg (lit.)
density 1.571 g/mL at 25 °C (lit.)
refractive index 1.3
Fp None
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Liquid
color Clear colorless
Specific Gravity1.571
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
BRN 1806446
Stability:Hygroscopic, Moisture Sensitive
InChIKeyXETRHNFRKCNWAJ-UHFFFAOYSA-N
CAS DataBase Reference356-42-3(CAS DataBase Reference)
NIST Chemistry ReferencePentafluoropropionic anhydride(356-42-3)
EPA Substance Registry SystemPentafluoropropionic anhydride (356-42-3)
Safety Information
Hazard Codes C
Risk Statements 34-14
Safety Statements 26-36/37/39-45
RIDADR UN 3265 8/PG 2
WGK Germany 3
10-21
Hazard Note Corrosive
TSCA T
HazardClass 8
PackingGroup II
HS Code 29159000
MSDS Information
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Perfluoropropionic anhydride Usage And Synthesis
Chemical PropertiesPerfluoropropionic anhydride is clear colorless liquid
UsesPentafluoropropionic anhydride was used:
  • in preparation of halogenated derivatives of phenolic acids, required for determination of some biologically important acids in cerebrospinal fluid
  • as derivatization reagent in detection of 1,2,3,4-tetrahydroisoquinoline and 1-methyl-1,2,3,4-tetrahydroisoquinoline as endogenous amines from non-treated rat brain by GC-multiple ion detection
  • in simultaneous determination of the major metabolites of dopamine in rat striatum by gas-liquid chromatography
UsesPentafluoropropionic anhydride act as a derivatising agent of amines and alcohols. It is used in the in preparation of halogenated derivatives of phenolic acids, required for determination of some biologically important acids in cerebrospinal fluid, as derivatization reagent in detection of 1,2,3,4-tetrahydroisoquinoline and 1-methyl-1,2,3,4-tetrahydroisoquinoline as endogenous amines from non-treated rat brain by GC-multiple ion detection and in simultaneous determination of the major metabolites of dopamine in rat striatum by gas-liquid chromatography.
UsesPerfluoropropionic anhydride used in a GC-MS analysis of stereoisomer content of synthetic peptides.1 Also used in a GC-MS detection method for synephrine in dietary supplements.2
Perfluoropropionic anhydride Preparation Products And Raw materials
Perfluorononanoic acid ETHYL PENTAFLUOROPROPIONYLACETATE SODIUM PENTAFLUOROPROPIONATE Pentafluoropyridine Acrylamide PENTAFLUOROPHENYLHYDRAZINE Heptafluorobutyric anhydride Trimellitic Anhydride Triethylamine 2,2,2-Trifluoroethanol Perfluoropropionic acid Pentafluorobenzaldehyde Tetrahydrofuran Perfluorooctyl iodide PENTAFLUOROTHIOPHENOL Propionic anhydride

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