Di-tert-butyl N,N-diisopropylphosphoramidite

Di-tert-butyl N,N-diisopropylphosphoramidite Basic information
Product Name:Di-tert-butyl N,N-diisopropylphosphoramidite
Synonyms:DI-T-BUTYL N,N-DIISOPROPYLPHOSPHORAMIDITE;DI-TERT-BUTYL-N,N-DIISOPROPYLPHOSPHOROAMIDITE;N,N-Bis(1-methylethyl)phosphoramidous Acid Bis(1,1-dimethylethyl)ester;N,N-BisisopropylphosphoraMidous acid bis(tert-butyl) ester;Di-tert-butyl N,N-diisopropylphosphoraMidite 95%;13748-86-8;Phosphoramidous acid,N,N-bis(1-methylethyl)-, bis(1,1-dimethylethyl) ester;di-tert-butyl diisopropylphosphoramide
CAS:137348-86-8
MF:C14H32NO2P
MW:277.38
EINECS:
Product Categories:Phosphorylating and Phosphitylating Agents;Catalysis and Inorganic Chemistry;Phosphine Ligands;Phosphorus Compounds;Phospholipids - 13C & 2H
Mol File:137348-86-8.mol
Di-tert-butyl N,N-diisopropylphosphoramidite Structure
Di-tert-butyl N,N-diisopropylphosphoramidite Chemical Properties
Boiling point 85-90 °C/0.2 mmHg (lit.)
density 0.879 g/mL at 25 °C (lit.)
refractive index n20/D 1.444(lit.)
Fp >230 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.90±0.70(Predicted)
form Liquid
color Clear colorless
BRN 4858847
Stability:Moisture Sensitive
InChIKeyYGFLCNPXEPDANQ-UHFFFAOYSA-N
CAS DataBase Reference137348-86-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
10-23
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
Di-tert-butyl N,N-diisopropylphosphoramidite Usage And Synthesis
Chemical PropertiesClear Colourless Liquid
UsesDi-tert-butyl N,N-diisopropylphosphoramidite is a general reagent to introduce tert-butyl-protected phosphate groups. It is commonly used in phosphorylation of biomolecules. It can also be used in the synthesis of phosphoramidate-linked glycoconjugates.
UsesA phosphinane derivative with immunomodulating activity.
Di-tert-butyl N,N-diisopropylphosphoramidite Preparation Products And Raw materials
Di-tert-butyl N,N-diethylphosphoramidite Di-tert-butyl N,N-diisopropylphosphoramidite DIETHYL N,N-DIISOPROPYLPHOSPHORAMIDITE

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