1,9-DIDEOXYFORSKOLIN

1,9-DIDEOXYFORSKOLIN Basic information
Product Name:1,9-DIDEOXYFORSKOLIN
Synonyms:7BETA-ACETOXY-8,13-EPOXY-6BETA-HYDROXY-LABD-14-EN-11-ONE;7BETA-ACETOXY-6BETA-HYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE;Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem;1,9-DIDEOXYFORSKOLIN;FORSKOLIN, 1,9-DIDEOXY;FORSKOLIN, 1,9-DIDEOXY-, COLEUS FORSKOHLII;1,9-DIDEOXYFORSKOLIN FROM COLEUSFORSKOHL II;FORSKOLIN, 1,9-DIDEOXY ISOLATED FROM COL EUS
CAS:64657-18-7
MF:C22H34O5
MW:378.5
EINECS:
Product Categories:
Mol File:64657-18-7.mol
1,9-DIDEOXYFORSKOLIN Structure
1,9-DIDEOXYFORSKOLIN Chemical Properties
Melting point 149-150℃
storage temp. −20°C
solubility methanol: 28 mg/mL
form solid
color white
optical activity[α]26/D +93.6°, c = 6.12 in chloroform(lit.)
InChIKeyZKZMDXUDDJYAIB-OJPJTMFRSA-N
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
1,9-DIDEOXYFORSKOLIN Usage And Synthesis
DescriptionForskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase.
Uses1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
DefinitionChEBI: A labdane diterpenoid that is the 1,9-dideoxy derivative of forskolin.
1,9-DIDEOXYFORSKOLIN Preparation Products And Raw materials
Sodium deoxycholate Forskolin DIDEOXYFORSKOLIN, 1,9-(RG) FORSKOLIN, [12-3H]- 1,9-DIDEOXYFORSKOLIN FORSKOLIN, 7-DEACETYL-7-O-HEMISUCCINYL- N,N-DIMETHYL-(3R,4AR,5S,6AS,10S,10AR,10BS)-5-(ACETYLOXY)-3-ETHENYLDODECAHYDRO-10,10B-DIHYDROXY-3,4A,7,7,10A-PENTAMETHYL-1-OXO-1H-NAPHTHO[2,1-B]PYRAN-6-YL ESTER B-ALANINE HYDROCHLORIDE FORSKOLIN, 6BETA-[BETA'-(PIPERIDINO)PROPIONYL]-, HYDROCHLORIDE 1-DEOXYFORSKOLIN FORSKOLIN, 7BETA-DEACETYL-7BETA-[GAMMA-(MORPHOLINO) BUTYRYL]-, HYDROCHLORIDE 7-deacetyl-1,9-dideoxyforskolin from coleus forskohlii

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