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| | 5-Nitrofurfural Basic information |
| | 5-Nitrofurfural Chemical Properties |
| Melting point | 37-39 °C(lit.) | | Boiling point | 121 °C10 mm Hg(lit.) | | density | 1.349 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.59(lit.) | | Fp | 92 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) | | form | Crystalline Low Melting Solid | | color | Yellow to brown | | Water Solubility | sparingly soluble | | Sensitive | Air & Light Sensitive | | BRN | 120539 | | InChIKey | SXINBFXPADXIEY-UHFFFAOYSA-N | | CAS DataBase Reference | 698-63-5(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Furancarboxaldehyde, 5-nitro-(698-63-5) |
| | 5-Nitrofurfural Usage And Synthesis |
| Description | Nitrofuran carboxaldehyde (NFC) is used to synthesize
many drugs and chemicals such as nifuraldezone, puraguanidine,
nifuratrone, furmethoxadone, etc. Furfural the
main structure of NFC was determined many years ago to be
a byproduct of formic acid synthesis. Furfural is produced
from agricultural byproducts such as sugarcane bagasse and
corncobs. | | Chemical Properties | Yellow to brown crystalline low melting solid | | Uses | NFC and its derivatives have antibacterial and antifungal
activities. They destroy both gram-positive and gram-negative
organisms such as Staphylococcus aureus, Salmonella schotmuelleri,
Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and
Streptococcus pyogenes. They may be used as antibacterial agents
in a prophylactic manner, for example, in cleaning and disinfecting
products. This compound also has antitrichomonal
and antifungal activities. | | Uses | 5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates. | | Definition | ChEBI: 5-Nitrofurfural is a C-nitro compound and a member of furans. | | Toxicity evaluation | NFC inhibits the uptake of oxygen and disrupts cellular respiration
within mitochondria. NFC and other nitrofurans are
relatively potent inhibitors of monoamine oxidase enzyme in
mammalian and avian species. |
| | 5-Nitrofurfural Preparation Products And Raw materials |
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