N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE

N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Basic information
Product Name:N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE
Synonyms:N-ACETYL-4-NITROPHENETHYLAMINE;N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE;N-[2-(4-NITROPHENYL)ETHYL]ACETAMIDE;n-(2-(p-nitrophenyl)ethyl)acetamide;n-[2-(4-nitrophenyl)ethyl]-acetamid;Acetylnitrophenylethylamine;N-(4-NITROPHENETHYL)ACETAMIDE;N-(4-NITROPHENYLETHYL)ACETAMID
CAS:6270-07-1
MF:C10H12N2O3
MW:208.21
EINECS:
Product Categories:
Mol File:6270-07-1.mol
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Structure
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Chemical Properties
Melting point 140°C
storage temp. 2-8°C
CAS DataBase Reference6270-07-1(CAS DataBase Reference)
EPA Substance Registry SystemAcetamide, N-[2-(4-nitrophenyl)ethyl]- (6270-07-1)
Safety Information
HS Code 2924.21.4500
MSDS Information
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Usage And Synthesis
Chemical PropertiesPale yellow powder
UsesN-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis3.png
450Kg of concentrated sulfuric acid was added to the reactor, the temperature of the reaction solution was room temperature, the reaction solution containing the intermediate 1 was slowly added dropwise, and after sufficient stirring, 75 kg of 70% nitric acid was slowly added. After stirring until completion of the reaction, 800kg of crushed ice was added to the reaction solution and stirred constantly , Finally, pH was adjusted to 7~8 with ammonia solution to give crude product after filtration, crude product was recrystallized from methyl ethyl ketone to give 140 Kg of Intermediate 2, with a yield of 81.5%.
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Preparation Products And Raw materials
Preparation ProductsAcetamide,N-[2-(4-aminophenyl)ethyl]--->4-Nitrophenethylamine hydrochloride
N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY Chloramphenicol palmitate HIV PROTEASE SUBSTRATE IV HIV PROTEASE SUBSTRATE VII N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE ANTHRANILYL-HIV PROTEASE SUBSTRATE IV LABOTEST-BB LT00441005 LABOTEST-BB LT00771854 2-ACETAMINO-1-P-NITROPHENYLETHANOL ABZ-GLY-4-NITRO-PHE-PRO-OH HIV PROTEASE SUBSTRATE III ANTHRANILYL-HIV PROTEASE SUBSTRATE III 4-NITRO-PHENETHYLAMINE BOC-PHE-ALA-ALA-4-NITRO-PHE-PHE-VAL-LEU-PYRIDIN-4-YLMETHYL ESTER Eusynthomycin CHLORAMPHENICOL (RING-D4, BENZYL-D1) chloramphenicol glucuronide H-PHE-GLY-HIS-P-NITRO-PHE-PHE-ALA-PHE-OME

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