Fmoc-O-trityl-L-threonine

Fmoc-O-trityl-L-threonine Basic information
Product Name:Fmoc-O-trityl-L-threonine
Synonyms:N-ALPHA-FMOC-O-TRITYL-L-THREONINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-TRITYL-L-THREONINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TRITYL-L-THREONINE;TRITYL-L-THREONINE;Fmoc-T(Trt)-OH;(2S,3R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(triphenylmethoxy)butanoic acid;O-Trityl-L-threonine, N-Fmoc protected;O-trityl-L-threonine, N-FMOC protected 98.5+%
CAS:133180-01-5
MF:C38H33NO5
MW:583.67
EINECS:
Product Categories:Threonine [Thr, T];Fmoc-Amino Acids and Derivatives;Amino Acids;Fmoc-Amino acid series
Mol File:133180-01-5.mol
Fmoc-O-trityl-L-threonine Structure
Fmoc-O-trityl-L-threonine Chemical Properties
Boiling point 753.0±60.0 °C(Predicted)
density 1.241±0.06 g/cm3(Predicted)
storage temp. Store at -15°C to -25°C.
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka3.31±0.10(Predicted)
CAS DataBase Reference133180-01-5(CAS DataBase Reference)
Safety Information
HS Code 2924297099
MSDS Information
Fmoc-O-trityl-L-threonine Usage And Synthesis
Chemical PropertiesWhite to off-white crystalline powder
General DescriptionThe side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphothreonine containing peptides and peptides modified at the threonine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2].

The product number for this product was previously 04-12-1141.

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Fmoc-O-trityl-L-threonine Preparation Products And Raw materials
Trityl candesartan METHOXYCARBONYLSULFENYL CHLORIDE N-alpha-FMOC-Nepsilon-BOC-L-Lysine p-Toluenesulfonic acid Fmoc-Asp(OtBu)-OH (-)-2-[METHYLAMINO]-1-PHENYLPROPANE CARBONYL SULFIDE Trityl candesartan cilexetil Nalpha-Fmoc-Ndelta-trityl-L-glutamine L-Threonine L-Fmoc-Aspartic acid alpha-tert-butyl ester 9-Fluorenylmethyl chloroformate Fmoc-Phe-OH Trityl Irbesartan Triphenylmethyl Chloride Fmoc 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid N-(9-Fluorenylmethoxycarbonyloxy)succinimide

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