|
| | ETH 1001 Basic information |
| Product Name: | ETH 1001 | | Synonyms: | (-)-(R,R)-N,N'-BIS[11-(ETHOXYCARBONYL)UNDECYL]-N,N',4,5-TETRAMETHYL-3,5-DIOXAOCTANEDIAMIDE;(-)-(R,R)-N,N'-BIS-[11-(ETHOXYCARBONYL)UNDECYL]-N,N'-4,5-TETRAMETHYL-3,6-DIOXAOCTANEDIAMIDE;CA 1001;CALCIUM IONOPHORE I;CALCIUM IONOPHORE;ETH 1001;DIETHYL-N,N'-[(4R,5R)-4,5-DIMETHYL-1,8-DIOXO-3,6-DIOXAOCTAMETHYLENE]BIS(12-METHYLAMINODODECANOATE);diethyl [R-(R*,R*)]-13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioate | | CAS: | 58801-34-6 | | MF: | C38H72N2O8 | | MW: | 684.99 | | EINECS: | 261-449-8 | | Product Categories: | | | Mol File: | 58801-34-6.mol |  |
| | ETH 1001 Chemical Properties |
| Boiling point | 715.1±50.0 °C(Predicted) | | density | 1.000±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Soluble in DMSO | | form | Light yellow, translucent, highly viscous oil | | pka | -0.52±0.70(Predicted) | | BRN | 2343275 |
| | ETH 1001 Usage And Synthesis |
| Description | Calcium ionophore I is a Ca2+-selective ionophore for biological membranes that can be used in microelectrodes for the determination of intracellular Ca2+-activities and of slowly changing Ca2+ levels. | | Purification Methods | This is a neutral Ca selectophore. It can be purified by thick layer (2mm) chromatography (Kieselgel F245) and eluted with Me2CO/CHCl3 (2:1). [Ammann et al. Helv Chim Acta 56 1780 1973, Simon & Carafoli Methods Enzymol 56 439 1977.] | | references | dagostino m, lee co. neutral carrier na+- and ca2+-selective microelectrodes for intracellular application. biophys j. 1982 dec;40(3):199-207.caroni p, gazzotti p, vuilleumier p, et al. ca2+ transport mediated by a synthetic neutral ca2+ -ionophore in biological membranes. biochim biophys acta. 1977 nov 1;470(3):437-45.hinds tr, vincenzi ff. the effect of eth 1001 on ion fluxes across red blood cell membranes. cell calcium. 1985 jun;6(3):265-79.lücke a, lehmenkühler a, speckmann ej. the influence of the convulsant pentylenetetrazol on ca2+-selective microelectrodes (neutral carrier eth 1001). j neurosci methods. 1989 aug;29(2):139-42.lee mh, yoo cl, lee js, et al. tweezer-type neutral carrier-based calcium-selective membrane electrode with drastically reduced anionic interference. anal chem. 2002 jun 1;74(11):2603-7. |
| | ETH 1001 Preparation Products And Raw materials |
|
