Methoxyphenamine

Methoxyphenamine Basic information
Product Name:Methoxyphenamine
Synonyms:Methoxyphenamine (base and/or unspecified salts);2-Methoxy-N,α-dimethylbenzeneethanamine;o-Methoxy-N,α-dimethylbenzeneethan-1-amine;o-Methoxy-N,α-dimethylbenzeneethanamine;o-Methoxy-α,N-dimethylbenzeneethanamine;2-Methoxyphenamine base;1-(2-Methoxyphenyl)-2-methylaminopropane;2-Methoxymethamphetamine
CAS:93-30-1
MF:C11H17NO
MW:179.25878
EINECS:202-237-7
Product Categories:
Mol File:93-30-1.mol
Methoxyphenamine Structure
Methoxyphenamine Chemical Properties
Melting point 271℃
Boiling point 252℃
density 0.951
Fp 103℃
pka10.36±0.10(Predicted)
Safety Information
MSDS Information
Methoxyphenamine Usage And Synthesis
Chemical PropertiesOily liquid. Boiling point 97-99 ℃ (0.267kPa). Its hydrochloride is a white crystalline powder with a melting point of 129-131 °C. Soluble in water, ethanol, chloroform, slightly soluble in benzene and ether. Odorless, bitter taste. The pH of a 5% aqueous solution is 5.3-5.7.
UsesMethoxyphenamine is an adrenaline-mimetic drug with significant bronchodilation and smooth muscle relaxation effects. It also has a mild antihistamine effect, a sedative effect and suppresses the cough center. It is suitable for treating bronchial asthma, especially for patients who cannot tolerate ephedrine.
DefinitionChEBI: Methoxyphenamine is an amphetamine methylated on nitrogen and with the phenyl ring methoxylated at C-2. A beta-adrenergic receptor agonist, it is used as a bronchodilator. It has a role as a beta-adrenergic agonist and a bronchodilator agent.
SynthesisMethoxyphenamine is obtained by methylation and reduction of o-methoxypropiophenone.
Methoxyphenamine Preparation Products And Raw materials
Raw materialsMethylamine-->Phenylacetone-->D/L-AMPHETAMINE HYDROCHLORIDE-->2-Methoxyphenylacetone
BW 737C89 5,8-dimethoxy-2-(2-hydroxyethyl)amino-3-hydroxy-1,2,3,4-tetrahydronaphthalene Butoxamine hydrochloride (+/-)-BUTOXAMINE SDZ NVI-085 cularine stephanine (S)-N-FMOC-(5-BROMO-2-METHOXYPHENYL)ALANINE Methoxyphenamine Pentamorphone Thalicarpine Tritoqualine ecteinascidin 743 SIBIRICINE 458L METHOXYPHENAMINE HCL ALNESPIRONE 8-M-PDOT

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