ChemicalBook Product Catalog Organic Chemistry Amides Acyclic polyamines and their derivatives N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI&

N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI&

N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Basic information
Product Name:N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI&
Synonyms:N-(3-Dimethylaminopropyl)-1,3-propanediamine;N-[3-(Dimethylamino)propyl]-1,3-propanediamine;1,3-Propanediamine, N3-(3-aminopropyl)-N1,N1-dimethyl-;Brn 2715375;Einecs 234-148-4;N,N-Dimethyldipropylenetriamine,DMAPAPA;N N'-DIMETHYLDIPROPY;N′-(3-Aminopropyl)-N,N-dimethyl-1,3-propandiamin
CAS:10563-29-8
MF:C8H21N3
MW:159.27
EINECS:234-148-4
Product Categories:Nitrogen Compounds;Organic Building Blocks;Polyamines
Mol File:10563-29-8.mol
N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Structure
N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Chemical Properties
Boiling point 220 °C(lit.)
density 0.883 g/mL at 25 °C(lit.)
vapor pressure 3Pa at 20℃
refractive index n20/D 1.4630(lit.)
Fp 220 °F
pka10.32±0.19(Predicted)
Water Solubility 1000g/L at 25℃
LogP-0.56 at 25℃
EPA Substance Registry System1,3-Propanediamine, N'-(3-aminopropyl)-N,N-dimethyl- (10563-29-8)
Safety Information
Hazard Codes C
Risk Statements 21/22-34
Safety Statements 23-26-36/37/39-45
RIDADR UN 2735 8/PG 2
WGK Germany 1
RTECS TX7000000
HazardClass 8
PackingGroup III
ToxicityLD50 orl-unr: 1432 mg/kg GTPZAB 28(11),50,84
MSDS Information
N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Usage And Synthesis
UsesN,N-Dimethyldipropylenetriamine (DP) may be used to:
  • Prepare poly(ethylene oxide)-b-poly(3-caprolactone-g-DP) [PEO-b-P(CL-g-DP)], a biodegradable amphiphilic polycationic copolymer.
  • Develop a second generation aminoglycoside 6′-N-acetyltransferase (AAC(6′) inhibitor.
  • Prepare a hydrophilic gemcitabine conjugated cationic copolymer, which can be employed in the treatment pancreatic cancer.
General DescriptionN,N-Dimethyldipropylenetriamine is an aliphatic acyclic amine that is commonly used to develop polymeric system for gene delivery.
Flammability and ExplosibilityNonflammable
Safety ProfileA poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.
N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& Preparation Products And Raw materials
N,N'-Dimethyl-1,3-propanediamine 3,3'-IMINOBIS(N,N-DIMETHYLPROPYLAMINE) BUTTPARK 8\03-08 2,6,10-TRIMETHYL-2,6,10-TRIAZAUNDECANE 1,5,9-TRIMETHYL-1,5,9-TRIAZACYCLOTRIDECANE N N'-DIMETHYLDIPROPYLENETRIAMINE (ATOFI& N,N'-DIMETHYL-2,6,10,14-TETRAAZAPENTADECANE 1,3,4,6,7,8-HEXAHYDRO-1-METHYL-2H-PYRIMIDOL[1,2-A]PYRIMIDINE 6,10-DIMETHYL-2,6,10,14-TETRAAZAPENTADECANE 3-(3-MALEIMIDOPROPYLCARBAMOYL)-PROXYL 1,5,9-TRIMETHYL-1,5,9-TRIAZACYCLODODECANE BUTTPARK 9\03-07 BUTTPARK 8\03-07 N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine MOSAPRAMINE Domperidone flumeridone carpipramine dihydrochloride
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