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| | Febantel Basic information |
| Product Name: | Febantel | | Synonyms: | Febantel powder;FEBANTEL PESTANAL;2-Acetamido-5-nitrothiazole VETRANAL;DIMETHYL[[2-[(METHOXYACETYL)AMINO]-4-(PHENYLTHIO)PHENYL]CARBONIMIDOYL]BISCARBAMATE(FEBANTEL);Febantel;N-{2-[2,3-Bis-(methoxycarbonyl)-guanido]-5-(phenylthio)-phenyl}-2-methoxyacetamide;Carbamicacid,[[2-[(methoxyacetyl)amino]-4-(phenylthio)phenyl]carbonimidoyl]bis-,dimethylester;n-(2-(2,3-bis-(methoxycarbonyl)-guanidino)-5-(phenylthio)-phenyl)-2-methoxya | | CAS: | 58306-30-2 | | MF: | C20H22N4O6S | | MW: | 446.48 | | EINECS: | 261-205-0 | | Product Categories: | Pharmaceutical intermediate;Intermediates & Fine Chemicals;Pharmaceuticals;58306-30-2 | | Mol File: | 58306-30-2.mol |  |
| | Febantel Chemical Properties |
| Melting point | 129-130°C | | Boiling point | 215°C (rough estimate) | | density | 1.2962 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Sparingly) | | form | neat | | pka | 7.60±0.46(Predicted) | | color | White to Off-White | | Merck | 14,3944 | | InChIKey | HMCCXLBXIJMERM-UHFFFAOYSA-N | | CAS DataBase Reference | 58306-30-2(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | RTECS | FB3955000 | | HS Code | 2930902000 |
| | Febantel Usage And Synthesis |
| Chemical Properties | Febantel is White to Off-White Solid
| | Originator | Rintal, Bayer,W. Germany,1979 | | Uses | Used as an anthelmintic. | | Uses | Febantel is used as an anthelmintic
| | Definition | ChEBI: Febantel is an aryl sulfide. | | Manufacturing Process | 2-Amino-5-phenylthiornethoxyacetanilide in methanol solution is heated with
N,N'-bis-methoxycarbonyl-isothiourea-S-methyl ether with the addition of a
catalytic amount of p-toluenesulfonic acid for three hours with stirring under
reflux. The mixture is then filtered hot and after cooling the febantel product
crystallizes out. It is filtered off, rinsed with ether and dried under high
vacuum to give the final product, melting at 129°C to 130°C. | | Brand name | Combotel (Bayer AnimalHealth); Negabot Plus Paste (Bayer Animal Health);
Oratel (Bayer Animal Health); Rintal (Bayer Animal
Health). | | Therapeutic Function | Anthelmintic |
| | Febantel Preparation Products And Raw materials |
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