7-HYDROXY QUETIAPINE

7-HYDROXY QUETIAPINE Basic information
Product Name:7-HYDROXY QUETIAPINE
Synonyms:7-Hydroxy Quetiapine Hemifumarate-d4;Quetiapine 7-Hydroxy Metabolite;7-HYDROXY QUETIAPINE;ICI214227;11-[4-[2-(2-Hydroxyethoxy)ethyl]-1-piperazinyl]-dibenzo[b,f][1,4]thiazepin-7-ol;2-(2-(7-hydroxy-4-dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol;7-Hydroxyquetiapine solution;11-(4-(2-(2-hydroxyethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepin-7-ol
CAS:139079-39-3
MF:C21H25N3O3S
MW:399.51
EINECS:
Product Categories:Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:139079-39-3.mol
7-HYDROXY QUETIAPINE Structure
7-HYDROXY QUETIAPINE Chemical Properties
Melting point 56-60°C
Boiling point 612.4±65.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
Fp 9℃
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka11.18±0.20(Predicted)
form Solid
color White to Pale Yellow
Stability:Hygroscopic
CAS DataBase Reference139079-39-3
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25
Safety Statements 16-36/37-45
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 1
MSDS Information
7-HYDROXY QUETIAPINE Usage And Synthesis
Chemical Properties7-HYDROXY QUETIAPINE is White Solid
Uses7-HYDROXY QUETIAPINE is a metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic
UsesA metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
General DescriptionA Certified Solution Standard for the primary active metabolite of quetiapine, marketed as the atypical antipsychotic Seroquel? for the treatment of depression, bipolar disorder, and schizophrenia. This new reference standard is suitable for a variety of GCMS and LCMS applications from forensic and forensic toxicology analyisis to urine drug testing. We also offer certified Snap-N-Shoot? solutions of the parent drug Quetiapine fumarate (Q-001) and the internal standard Quetiapine-D8 hemifumarate (Q-002) as well as a wide selection of other atypical antipsychotics and their metabolites and internal standards, such as aripiprazole, clozapine, risperidone, olanzapine, and ziprasidone.
7-HYDROXY QUETIAPINE Preparation Products And Raw materials
PHENYL N-(2-CHLOROPHENYL)CARBAMATE N-(2-((2-(4-(2-(2-Hydroxyethoxy)ethyl)piperazine-1-carbonyl)phenyl)thio)phenyl)acetaMide 2-[2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethoxy]ethanol FuMarate Quetiapine Thiocarbonic acid O,S-diphenyl ester Quetiapine Carboxylate Impurity Ethyl Quetiapine Fumarate Salt Quetiapine fumarate 7-Hydroxy Quetiapine-D8 11-(1-PIPERAZINYL)-DIBENZO[B,F][1,4]THIAZEPIN-7-OL 7-HYDROXY QUETIAPINE 11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE

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