CHRYSOMYCIN A

CHRYSOMYCIN A Basic information
Product Name:CHRYSOMYCIN A
Synonyms:6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-(9CI);8-ethenyl-1-hydroxy-10,12-dimethoxy-4-(3,4,5-trihydroxy-4,6-dimethyloxan-2-yl)naphtho[1,2-c]isochromen-6-one;(+)-4-(6-Deoxy-3-C-methyl-β-D-gulo-hexopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one;(+)-Virenomycin V;Chrysomycin V;Virenomycin V;4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one;NSC 613946
CAS:82196-88-1
MF:C28H28O9
MW:508.52
EINECS:
Product Categories:Inhibits an EnzymeEnzyme Inhibitors by Enzyme;Topoisomerase II;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Antibiotics by Application;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Mechanism of Action;R to;Spectrum of Activity
Mol File:82196-88-1.mol
CHRYSOMYCIN A Structure
CHRYSOMYCIN A Chemical Properties
Boiling point 799.7±60.0 °C(Predicted)
density 1.405±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: soluble
form solid
pka8.55±0.20(Predicted)
color Yellow to greenish
Safety Information
WGK Germany 3
MSDS Information
CHRYSOMYCIN A Usage And Synthesis
UsesChrysomycin A is the major analogue in a complex of C-glycoside antitumour actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomyin A has a potent antibacterial, antifungal, antiviral and antitumour profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated, crosslinkers of DNA to histones.
UsesChrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomycin A has a potent antibacterial, antifungal, antiviral and antitumor profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated cross-linkers of DNA to histones.
UsesChrysomycin A is a potent antibacterial, antifungal and antiviral compound.
DefinitionChEBI: Chrysomycin a is a glycoside.
storage+4°C
CHRYSOMYCIN A Preparation Products And Raw materials
Flavomycin 2-BIPHENYL-(3'-METHOXY)CARBOXYLIC ACID CHRYSOMYCIN A CHRYSOMYCIN B 2,5-DIMETHYL-3-HYDROXY BENZOIC ACID Menadiol monoacetate 2,5-DIHYDROXY-4'-METHYLBIPHENYL 1-METHOXYNAPHTHALEN-4-YL ACETATE 1-naphthyl benzoate

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