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| | 4-Bromobiphenyl Basic information |
| | 4-Bromobiphenyl Chemical Properties |
| Melting point | 82-86 °C(lit.) | | Boiling point | 310 °C(lit.) | | density | 0.9327 | | refractive index | 1.6565 (estimate) | | Fp | 143 °C | | storage temp. | Sealed in dry,Room Temperature | | solubility | dioxane: soluble1g/10 mL, clear, colorless to very faintly yellow | | form | Crystalline Flakes | | color | Almost white to slightly yellow | | Water Solubility | Insoluble | | BRN | 1907453 | | Stability: | Stable. Incompatible with oxidizing agents. | | InChIKey | PKJBWOWQJHHAHG-UHFFFAOYSA-N | | CAS DataBase Reference | 92-66-0(CAS DataBase Reference) | | NIST Chemistry Reference | 1,1'-Biphenyl, 4-bromo-(92-66-0) | | EPA Substance Registry System | 4-Bromobiphenyl (92-66-0) |
| | 4-Bromobiphenyl Usage And Synthesis |
| Chemical Properties | White powder | | Uses | 4-Bromobiphenyl is used as a reagent in the synthesis of spirooxindole derivatives for use as AMPK activators. It is also used as a reagent in the preparation of indenoindole derivatives as organic electroluminescent device materials. | | Uses | 4-Bromobiphenyl is used as halogenated hydrocarbon and Intermediates of Liquid Crystals. It is also used in used in the synthesis of 4-biphenylthiolate. | | General Description | Colorless crystals. Insoluble in water. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | 4-Bromobiphenyl may be sensitive to light, and it can react with oxidizing materials. | | Fire Hazard | Combustible. | | Synthesis |
Into a 250 ml reactor equipped with magnetic agitation means, a condenser, a dropping funnel, and a thermometer, the following materials were introduced:
(i) 15.4 g biphenyl (0.1 M);
(ii) 100 ml solvent
at ambient temperature Then, over 10 min, the bromine was poured therein (39.2 g/0.22 M), whereupon the mixture was agitated for a varying period of time at ambient temperature. Upon completion of the reaction, the excess bromine was consumed by sodium or potassium sulfite or bisulfite. The organic phase was washed, dried and diluted to a given volume, and analyzed by CPG to give 4-Bromobiphenyl.
| | Purification Methods | Crystallise the biphenyl from abolute EtOH and dry it in vacuo.[Beilstein 5 IV 1819.] |
| | 4-Bromobiphenyl Preparation Products And Raw materials |
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